search engines like google Endodan (Oral) Generic Name: oxycodone and aspirin (Oral route) AS-pir-in, ox-i-KOE-done hye-droe-KLOR-ide Oral route(Tablet) Oxycodone hydrochloride/aspirin has the potential for addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient's risk before prescribing, and monitor for development of these behaviors or conditions. Serious, life-threatening, or fatal respiratory depression may occur. Monitor closely, especially upon initiation or following a dose increase. Accidental ingestion of oxycodone hydrochloride/aspirin, especially in children, can result in fatal overdose of oxycodone hydrochloride. Prolonged use of oxycodone hydrochloride/aspirin during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available. Concomitant use or discontinuation of concomitantly used cytochrome P450 3A4 inhibitors and inducers may affect the plasma levels of oxycodone and lead to fatal respiratory depression, profound sedation, opioid toxicity, and/or opioid withdrawal. Monitor patients carefully when oxycodone hydrochloride/aspirin and cytochrome P450 3A4 inhibitors and inducers are concurrently used. Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for patients with inadequate alternative treatment options. Limit dosages and durations to the minimum required and follow patients for signs and symptoms of respiratory depression and sedation . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Commonly used brand name(s) In the U.S. Endodan Percodan Available Dosage Forms: Tablet Therapeutic Class: Opioid/Salicylate, Aspirin Combination Pharmacologic Class: NSAID Chemical Class: Salicylate, Aspirin Slideshow Upcoming Joint Replacement? Your 13 Most Common Questions Answered Uses For Endodan Oxycodone and aspirin combination is used to relieve moderate to moderately severe pain. Oxycodone belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain. Aspirin is used to relieve pain and reduce fever in patients. Aspirin belongs to the group of medicines known as salicylates and acts on the immune system to reduce inflammation. It is also known as an antiinflammatory analgesic. When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. This medicine is available only with your doctor's prescription. Before Using Endodan In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of oxycodone and aspirin combination in the pediatric population. Because of aspirin's toxicity, use in children is not recommended. Do not give aspirin to a child who has chickenpox or flu symptoms, unless approved by a doctor. Aspirin can cause a life-threatening reaction called Reye syndrome. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of oxycodone and aspirin combination in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or lung problems, which may require caution and an adjustment in the dose for patients receiving oxycodone and aspirin combination. Breast Feeding Aspirin There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Oxycodone Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Amifampridine Defibrotide Dichlorphenamide Influenza Virus Vaccine, Live Ketorolac Nalmefene Naltrexone Safinamide Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Abiraterone Acarbose Aceclofenac Acemetacin Acepromazine Alfentanil Alipogene Tiparvovec Almotriptan Alprazolam Alteplase, Recombinant Alvimopan Amiloride Amineptine Amiodarone Amisulpride Amitriptyline Amitriptylinoxide Amobarbital Amoxapine Amphetamine Amprenavir Amtolmetin Guacil Anagrelide Anileridine Anisindione Apixaban Aprepitant Argatroban Aripiprazole Asenapine Atazanavir Baclofen Bendroflumethiazide Benperidol Benzphetamine Benzthiazide Betrixaban Bivalirudin Boceprevir Bromazepam Bromfenac Bromopride Brompheniramine Bufexamac Bumetanide Buprenorphine Buspirone Butabarbital Butorphanol Carbamazepine Carbinoxamine Carisoprodol Carphenazine Celecoxib Ceritinib Chloral Hydrate Chlordiazepoxide Chlorothiazide Chlorpheniramine Chlorpromazine Chlorpropamide Chlorthalidone Chlorzoxazone Choline Salicylate Cilostazol Citalopram Clarithromycin Clobazam Clomipramine Clonazepam Clonixin Clopamide Clopidogrel Clorazepate Clozapine Cobicistat Cocaine Codeine Conivaptan Cyclobenzaprine Cyclopenthiazide Cyclosporine Dabigatran Etexilate Danaparoid Darunavir Desipramine Desirudin Desmopressin Desvenlafaxine Dexibuprofen Dexketoprofen Dexmedetomidine Dextroamphetamine Dextromethorphan Dezocine Diazepam Diazoxide Dibenzepin Dichloralphenazone Diclofenac Dicumarol Difenoxin Diflunisal Digoxin Dihydrocodeine Diphenhydramine Diphenoxylate Dipyrone Dolasetron Donepezil Dothiepin Doxepin Doxylamine Droperidol Droxicam Duloxetine Edoxaban Eletriptan Enflurane Enzalutamide Eplerenone Eptifibatide Erythromycin Escitalopram Estazolam Eszopiclone Ethacrynic Acid Ethchlorvynol Ethopropazine Ethylmorphine Etodolac Etofenamate Etoricoxib Felbinac Fenoprofen Fentanyl Fepradinol Feprazone Feverfew Flibanserin Floctafenine Flufenamic Acid Fluoxetine Fluphenazine Flurazepam Flurbiprofen Fluspirilene Fluvoxamine Fondaparinux Fosaprepitant Fosphenytoin Fospropofol Frovatriptan Furazolidone Furosemide Ginkgo Glimepiride Glipizide Glyburide Gossypol Granisetron Halazepam Haloperidol Halothane Heparin Hexobarbital Hydrochlorothiazide Hydrocodone Hydroflumethiazide Hydromorphone Hydroxytryptophan Hydroxyzine Ibuprofen Idelalisib Imipramine Indapamide Indinavir Indomethacin Iproniazid Isocarboxazid Isoflurane Itraconazole Ketamine Ketazolam Ketobemidone Ketoconazole Ketoprofen Lepirudin Levomilnacipran Levorphanol Linezolid Lisdexamfetamine Lithium Lofepramine Lopinavir Lorazepam Lorcaserin Lornoxicam Loxapine Loxoprofen Lumacaftor Lumiracoxib Meclizine Meclofenamate Mefenamic Acid Melitracen Meloxicam Melperone Meperidine Mephobarbital Meprobamate Meptazinol Mesoridazine Metaxalone Metformin Methadone Methamphetamine Methdilazine Methocarbamol Methohexital Methotrexate Methotrimeprazine Methyclothiazide Methylene Blue Methylnaltrexone Metolazone Midazolam Milnacipran Mirtazapine Mitotane Moclobemide Molindone Moricizine Morniflumate Morphine Morphine Sulfate Liposome Nabumetone Nalbuphine Nalorphine Naloxone Naproxen Naratriptan Nateglinide Nefazodone Nelfinavir Nepafenac Nialamide Nicomorphine Nicorandil Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Nitrazepam Nitrous Oxide Nortriptyline Olanzapine Ondansetron Opipramol Opium Opium Alkaloids Orphenadrine Oxaprozin Oxazepam Oxymorphone Oxyphenbutazone Palonosetron Papaveretum Parecoxib Paregoric Paroxetine Pemetrexed Pentazocine Pentobarbital Pentosan Polysulfate Sodium Pentoxifylline Perampanel Perazine Periciazine Perphenazine Phenelzine Phenindione Phenobarbital Phenprocoumon Phenylbutazone Phenytoin Piketoprofen Pimozide Piperacetazine Pipotiazine Piracetam Piritramide Piroxicam Polythiazide Posaconazole Pralatrexate Pranoprofen Prasugrel Prazepam Primidone Procarbazine Prochlorperazine Proglumetacin Promazine Promethazine Propofol Propyphenazone Proquazone Protein C Protriptyline Quazepam Quetiapine Ramelteon Rasagiline Remifentanil Remoxipride Repaglinide Reteplase, Recombinant Ribociclib Ritonavir Rivaroxaban Rizatriptan Rofecoxib Salicylic Acid Salsalate Samidorphan Saquinavir Secobarbital Selegiline Sertindole Sertraline Sibutramine Sodium Oxybate Sodium Salicylate Spironolactone Sufentanil Sulindac Sulpiride Sumatriptan Suvorexant Tacrolimus Tapentadol Telaprevir Telithromycin Temazepam Tenoxicam Thiethylperazine Thiopental Thiopropazate Thioridazine Tianeptine Tiaprofenic Acid Ticagrelor Ticlopidine Tilidine Tirofiban Tizanidine Tolazamide Tolbutamide Tolfenamic Acid Tolmetin Tolonium Chloride Topiramate Torsemide Tramadol Tranylcypromine Trazodone Treprostinil Triamterene Triazolam Trichlormethiazide Trifluoperazine Trifluperidol Triflupromazine Trimeprazine Trimipramine Tryptophan Valdecoxib Varicella Virus Vaccine Venlafaxine Vilazodone Vortioxetine Warfarin Xipamide Zaleplon Ziprasidone Zolmitriptan Zolpidem Zopiclone Zotepine Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acebutolol Atenolol Betamethasone Betaxolol Bisoprolol Captopril Carteolol Carvedilol Celiprolol Cortisone Delapril Dexamethasone Enalaprilat Enalapril Maleate Esmolol Imidapril Labetalol Levobunolol Lisinopril Methylprednisolone Metipranolol Metoprolol Miconazole Nadolol Nebivolol Nitroglycerin Oxprenolol Paramethasone Penbutolol Pindolol Practolol Prednisolone Prednisone Probenecid Propranolol Rifampin Sotalol St John's Wort Streptokinase Tamarind Temocapril Tenecteplase Timolol Triamcinolone Valproic Acid Voriconazole Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Ethanol Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Ethanol Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Addison disease (adrenal gland problem) or Alcohol abuse, or history of or Bleeding problems or Brain tumor, history of or Chronic obstructive pulmonary disease (COPD) or Cor pulmonale (serious heart condition) or Drug dependence, especially with narcotics, or history of or Gallbladder disease or gallstones or Head injury, history of or Hypothyroidism (an underactive thyroid) or Hypovolemia (low blood volume) or Kyphoscoliosis (curvature of the spine with breathing problems) or Peptic ulcer disease, active or history of or Problems with passing urine or Prostatic hypertrophy (enlarged prostate, BPH) or Vitamin K deficiency Use with caution. May increase risk for more serious side effects. Hemophilia or Lung disease or breathing problems (eg, respiratory depression), severe or Stomach or bowel blockage (eg, paralytic ileus) or Viral infection Should not be used in patients with these conditions. Hypotension (low blood pressure) or Pancreatitis (inflammation of the pancreas) or Seizures, history of Use with caution. May make these conditions worse. Kidney disease or Liver disease Use with caution. The effects may be increased because of slower removal of the medicine from the body. Proper Use of oxycodone and aspirin This section provides information on the proper use of a number of products that contain oxycodone and aspirin. It may not be specific to Endodan. Please read with care. Take this medicine only as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence). This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For moderate to moderately severe pain: Adults One tablet every 6 hours as needed. Your doctor may adjust your dose if needed. However, the dose is usually not more than 12 tablets per day. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Store the medicine in a safe and secure place. Do not throw unused medicine in the trash. Ask your pharmacist about the best way to dispose of medicine you do not use. Precautions While Using Endodan It is very important that your doctor check your progress while you are taking this medicine . This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away. Check with your doctor before using Percodan with alcohol or other medicines that affect the central nervous system (CNS) . The use of alcohol or other medicines that affect the CNS with Percodan may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Do not use more of this medicine or take it more often than your doctor tells you to. This can be life-threatening . Symptoms of an overdose include extreme dizziness or weakness, slow heartbeat or breathing, seizures, trouble breathing, and cold, clammy skin. Call your doctor right away if you notice these symptoms. This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions. Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness. This medicine may make you dizzy, drowsy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert . Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems. Check with your doctor right away if you have the following symptoms while using this medicine: acid or sour stomach, bloody or black, tarry stools, heartburn, nausea, vomiting, stomach pain, or vomiting of blood or material that looks like coffee grounds. This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine. Using this medicine while you are pregnant may cause neonatal withdrawal syndrome in your newborn babies. Tell your doctor right away if your baby has an abnormal sleep pattern, diarrhea, a high-pitched cry, irritability, shakiness or tremors, weight loss, vomiting, or fails to gain weight. Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body. Using too much of this medicine may cause infertility (unable to have children). Talk with your doctor before using this medicine if you plan to have children. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Endodan Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Incidence not known Abdominal pain, cramping, or tenderness agitation bleeding gums bloating blood in the urine or stools bloody, black, or tarry stools blue lips, fingernails, or skin blurred vision burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings change in consciousness or confusion chest pain or discomfort chills clay-colored stools constipation convulsions coughing or vomiting blood dark-colored urine decrease in urine volume or frequency decreased appetite depression difficult, fast, noisy breathing, sometimes with wheezing difficulty in passing urine (dribbling) dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position drowsiness dry mouth fainting fast, slow, irregular, pounding, or racing heartbeat or pulse feeling of hostility or irritability feeling of warmth feeling that something terrible will happen fever headache, sudden, severe heartburn hives, itching, or skin rash increased menstrual flow or vaginal bleeding increased sweating indigestion irregular, fast, slow, or shallow breathing large, flat, blue or purplish patches in the skin large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs loss of consciousness muscle cramping, weakness, or tremors muscle pain or stiffness nausea or vomiting nosebleeds numbness or tingling in the hands, feet, or lips painful or difficult urination pains in the stomach, side, or abdomen, possibly radiating to the back pale skin pinpoint red or purple spots on the skin prolonged bleeding from cuts puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue red or black, tarry stools or dark urine restlessness shivering sleepiness sunken eyes sweating swelling of face, ankles, hands, feet, or lower legs thirst tightness in the chest unusual bleeding or bruising unusual tiredness or weakness vomiting of material that looks like coffee grounds, severe and continuing weak or feeble pulse weakness or heaviness of the legs weight gain wrinkled skin yellow eyes or skin Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Continuing ringing or buzzing or other unexplained noise in the ears decreased awareness or responsiveness diarrhea drowsiness enlarged pupils extremely high fever or body temperature fast, weak heartbeat hearing loss increase in heart rate restlessness severe sleepiness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Relaxed and calm feeling sleepiness Incidence not known Belching bloated, full feeling blurred or loss of vision change in color perception cold sweats constricted, pinpoint, or small pupils (black part of the eye) cool, pale skin double vision excess air or gas in the stomach false or unusual sense of well-being flushed, dry skin fruit-like breath odor halos around lights increased hunger or thirst increased urination lack or loss of strength night blindness nightmares overbright appearance of lights red eyes redness of the skin seeing, hearing, or feeling things that are not there shakiness sleepiness or unusual drowsiness slurred speech trouble sleeping tunnel vision unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness weight loss Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. 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Next Side Effects Print this page Add to My Med List More about Endodan (aspirin / oxycodone) Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: narcotic analgesic combinations Consumer resources Endodan Other brands: Percodan Professional resources Endodan (FDA) Related treatment guides Pain} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans 2 CSA Schedule High potential for abuse WADA Class Anti-Doping Classification Manufacturer Endo Pharmaceuticals Inc. Drug Class Narcotic analgesic combinations Related Drugs Pain tramadol , acetaminophen , Tylenol , naproxen , oxycodone , aspirin , ibuprofen , amitriptyline , hydrocodone , clonidine , Norco , diclofenac , Percocet , hydroxyzine , Voltaren , lidocaine topical , Aleve , Celebrex , morphine , acetaminophen / hydrocodone , fentanyl , diphenhydramine topical , Advil , More... Endodan Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Endodan Images Endodan aspirin 325 mg / oxycodone hydrochloride 4.8355 mg (Endo 610 ) View larger images Help and Support Looking for answers? Ask a question or go join the Endodan support group to connect with others who have similar interests.} } most useful
first-rate Endodan (Oral) is widely known
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