they bring Apokyn (Subcutaneous) Generic Name: apomorphine (Subcutaneous route) a-poe-MOR-feen Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Apokyn Available Dosage Forms: Solution Therapeutic Class: Antiparkinsonian Pharmacologic Class: Dopamine Agonist Slideshow View Frightful (But Dead Serious) Drug Side Effects Uses For Apokyn Apomorphine is used to treat Parkinson's disease, sometimes referred to as "shaking palsy." By improving muscle control and reducing stiffness, this medicine allows more normal movements of the body as the disease symptoms are reduced . This medicine is available only with your doctor's prescription . Before Using Apokyn In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of apomorphine in children with use in other age groups . Geriatric Confusion, hallucinations, falls causing bone and joint injuries, heart, lung, or stomach problems may be especially likely to occur in elderly patients, who are usually more sensitive than younger adults to the effects of apomorphine . Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Alosetron Amifampridine Amisulpride Bepridil Cisapride Dolasetron Dronedarone Granisetron Mesoridazine Ondansetron Palonosetron Pimozide Piperaquine Saquinavir Sparfloxacin Sulpiride Terfenadine Thioridazine Ziprasidone Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Alfuzosin Amiodarone Amitriptyline Amoxapine Anagrelide Aripiprazole Aripiprazole Lauroxil Arsenic Trioxide Asenapine Astemizole Azithromycin Buserelin Chloroquine Chlorpromazine Ciprofloxacin Citalopram Clarithromycin Clomipramine Clozapine Crizotinib Dabrafenib Dasatinib Degarelix Delamanid Desipramine Deslorelin Deutetrabenazine Disopyramide Dofetilide Domperidone Donepezil Droperidol Efavirenz Entacapone Erythromycin Escitalopram Fingolimod Flecainide Fluconazole Fluoxetine Foscarnet Gatifloxacin Gemifloxacin Gonadorelin Goserelin Halofantrine Haloperidol Histrelin Hydroxychloroquine Hydroxyzine Ibutilide Iloperidone Imipramine Ivabradine Ketoconazole Lapatinib Leuprolide Levofloxacin Lopinavir Lumefantrine Mefloquine Methadone Metronidazole Moxifloxacin Nafarelin Nilotinib Norfloxacin Nortriptyline Octreotide Ofloxacin Paliperidone Panobinostat Pasireotide Pazopanib Pimavanserin Pitolisant Posaconazole Procainamide Prochlorperazine Promethazine Propafenone Protriptyline Quetiapine Quinidine Quinine Ranolazine Ribociclib Salmeterol Sevoflurane Sodium Phosphate Sodium Phosphate, Dibasic Sodium Phosphate, Monobasic Solifenacin Sorafenib Sotalol Sunitinib Tacrolimus Telavancin Telithromycin Tetrabenazine Toremifene Trazodone Trifluoperazine Triptorelin Vandetanib Vardenafil Vemurafenib Vinflunine Voriconazole Zuclopenthixol Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Dyskinesia (difficulty performing voluntary movements without tics and spasms) May be worsened by apomorphine . Heart disease or problems or Hypokalemia (abnormally low potassium in the blood) or Hypomagnesemia (abnormally low magnesium in the blood) or Stroke Extra caution should be used because heart problems have been reported with apomorphine use . Kidney problems The starting dose of apomorphine will need to be reduced . Liver problems Caution should be used because the amount of apomorphine in the blood may be increased . Psychotic disorder The doctor needs to know if the patient is being treated with an antipsychotic medicine to decide whether or not to use this medicine . Sleeping disorder This medicine could increase the risk of being drowsy or sleepy during daily activities . Proper Use of Apokyn Some medicines given by injection may sometimes be given at home to patients who do not need to be in the hospital. If you are using this medicine at home, make sure you clearly understand and carefully follow your doctor's instructions . Use this medicine only as directed by your doctor. Do not use more or less of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of side effects . This medicine should be injected just under the skin (i.e., subcutaneously), and not into a vein (i.e., intravenously) . Your doctor will also prescribe another medicine called an antiemetic to take when you are using apomorphine. Antiemetic medicines help reduce the nausea and vomiting that can occur with apomorphine use . Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For parenteral dosage form (injection): For treatment of Parkinson's disease: Adults Your doctor will use a test dose of 0.2 mL and base your starting dose on how your body responds to the test dose . Children Use and dose must be determined by your doctor . Missed Dose Call your doctor or pharmacist for instructions. Storage Keep out of the reach of children. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Apokyn When you are using apomorphine, you should avoid drinking alcohol . Do not take medicines that cause sleepiness while taking apomorphine . Do not take other medicines unless they have been discussed with your doctor . If you take too much apomorphine, you may experience more side effects or they may be stronger than usual. You should contact your doctor or have someone take you to an emergency room right away . Tell your doctor if you are having trouble with drowsiness and sleepiness during the day . This medicine may cause some people to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert . Do not get up too quickly from a lying or sitting position. This could cause dizziness and faintness to occur . Apokyn Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Chest pain, discomfort, or pressure chills cold sweats confusion dizziness, faintness, or light-headedness when getting up from lying or sitting position falling asleep during activity mood or mental changes seeing, hearing, or feeling things that are not there swelling twitching, twisting, uncontrolled repetitive movements of tongue, lips, face, arms, or legs Less common Arm, back, neck or jaw pain or discomfort chest tightness or heaviness fainting fast or irregular heartbeat low blood pressure or pulse nausea shortness of breath sweating unconsciousness vomiting Rare Irregular heartbeat recurrent fainting Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at injection site blurred vision dizziness drowsiness runny nose sleepiness yawning Rare Painful or prolonged erection of the penis Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. 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Next Side Effects Print this page Add to My Med List More about Apokyn (apomorphine) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 3 Reviews Add your own review/rating Drug class: dopaminergic antiparkinsonism agents Consumer resources Apokyn Professional resources Apokyn (AHFS Monograph) Apokyn (FDA) Related treatment guides Parkinson's Disease} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Dopaminergic antiparkinsonism agents Related Drugs Parkinson's Disease Exelon , ropinirole , pramipexole , Sinemet , Requip , benztropine , carbidopa / levodopa , Mirapex , amantadine , rivastigmine , Azilect , Cogentin , selegiline , trihexyphenidyl , bromocriptine , entacapone , Neupro , Rytary , rasagiline , Stalevo , Artane , carbidopa / entacapone / levodopa , Comtan , belladonna , More... Apokyn Rating 3 User Reviews 7.3 /10 3 User Reviews 7.3 Rate it! Related Questions & Answers Has apokyn ever been tested for essential tremors and if not would you like a willing subject? Read more questions} } significantly
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