you will likely gadoterate (Intravenous route) gad-oh-TER-ate MEG-loo-meen Intravenous route(Solution) Gadolinium-based contrast agents (GBCAs) increase the risk for nephrogenic systemic fibrosis (NSF) among patients with impaired elimination of the drugs. Avoid use of GBCAs in these patients unless the diagnostic information is essential and not available with noncontrasted MRI or other modalities. NSF may result in fatal or debilitating fibrosis affecting the skin, muscle, and internal organs. The risk for NSF appears highest among patients with chronic, severe kidney disease (GFR less than 30 mL/min/1.73m(2)), or acute kidney injury. Screen patients for acute kidney injury and other conditions that may reduce renal function. For patients at risk for chronically reduced renal function (eg, older than 60 years, hypertension, diabetes), estimate the glomerular filtration rate (GFR) through laboratory testing . Overview Side Effects Interactions Reviews Q & A More Commonly used brand name(s) In the U.S. Dotarem Available Dosage Forms: Solution Slideshow Mammogram Memos: What You Need To Know Uses For gadoterate Gadoterate is a magnetic resonance imaging (MRI) contrast agent. Contrast agents are used to help create a clear picture of the body during MRI scans. MRI scans are a special kind of diagnostic procedure. They use magnets and computers to create images or pictures of certain areas inside the body. Unlike x-rays, they do not involve ionizing radiation. Gadoterate is a gadolinium-based contrast agent (GBCA). Gadoterate is given by injection before MRI to help diagnose problems in the brain, spine, head, neck, and other parts of your body. gadoterate is to be used only by or under the direct supervision of a doctor. Before Using gadoterate In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For gadoterate, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to gadoterate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of gadoterate in children 2 years of age and older. However, safety and efficacy have not been established in children younger than 2 years of age. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of gadoterate in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution in patients receiving gadoterate. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of gadoterate. Make sure you tell your doctor if you have any other medical problems, especially: Asthma or allergies, history of or Patients who have had prior reactions to contrast media Use with caution. May increase the likelihood of an allergic reaction. Diabetes or Hypertension (high blood pressure) Use with caution. May increase your likelihood of having reduced kidney function. Kidney disease, mild or moderate Use with caution. May increase the likelihood of serious side effects. Kidney problems, severe (acute or long-term) Should not be used in patients with this condition. Proper Use of gadoterate A doctor or other trained health professional will give you or your child gadoterate. gadoterate is given through a needle placed in one of your veins just before you have an MRI scan. Precautions While Using gadoterate It is very important that your doctor check the progress of you or your child while you are receiving gadoterate and during the MRI scan . This will allow your doctor to see if the medicine is working properly and to check for unwanted effects. The risk of having a very serious disease called nephrogenic systemic fibrosis (NSF) is increased in patients with severe kidney disease. Even if you have severe kidney problems, your doctor may decide that it is still important to use gadoterate. Check with your doctor right away if you or your child have burning or itching of the skin, red or dark patches on the skin, swelling, hardening, or tightening of the skin, joint stiffness, limited range of motion in the arms and legs, pain that is deep in the hip bone or ribs, or muscle weakness . These may be symptoms of NSF. gadoterate may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Check with your doctor or nurse right away if you or your child have cold, clammy skin, confusion, dizziness, lightheadedness, a skin rash, itching, sweating, swelling of the face, tongue, and throat, trouble with breathing, or chest pain after you receive the medicine. Tell your doctor right away if you or your child have mild, burning pain, feeling of warmth or coldness, peeling of the skin, redness, or swelling at the injection site. gadoterate Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: Rare Blurred vision dizziness fast, irregular, pounding, or racing heartbeat or pulse headache nervousness pounding in the ears slow or fast heartbeat Incidence not known Areas of the skin that turn red or dark or feel tight bluish color of the fingernails, lips, skin, palms, or nail beds bone pain in the hips or ribs burning, dry, or itching eyes change in consciousness chest pain or discomfort cough difficulty with swallowing discharge or excessive tearing fainting fever hives or welts increased sweating itching large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs lightheadedness, dizziness, or fainting loss of consciousness muscle weakness no blood pressure or pulse no breathing puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue redness of the skin redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid shakiness in the legs, arms, hands, or feet skin rash skin that burns or itches, swells, scales, or hardens stiff joints or muscles stopping of the heart trembling or shaking of the hands or feet trouble moving your arms or legs unconsciousness unusual tiredness or weakness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Rare Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings change in taste discomfort in the throat fear loss of taste nausea pain in the arms or legs pain, burning, or cold sensation at the injection site sleepiness or unusual drowsiness vomiting Incidence not known Transient, mild, pleasant aromatic odor Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about gadoterate meglumine Side Effects Drug Interactions Support Group 0 Reviews Add your own review/rating Drug class: magnetic resonance imaging contrast media Consumer resources Gadoterate Meglumine Other brands: Dotarem Professional resources Related treatment guides CNS Magnetic Resonance Imaging} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Magnetic resonance imaging contrast media Related Drugs CNS Magnetic Resonance Imaging Magnevist , gadobutrol , gadobenate dimeglumine , Gadavist , Multihance , Prohance , Omniscan , gadoterate meglumine , Dotarem , gadoteridol , gadodiamide , More... Gadoterate meglumine Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? 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