appropriate aripiprazole lauroxil (Intramuscular route) ar-i-PIP-ra-zole lawr-OX-il Intramuscular route(Suspension, Extended Release) Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Aripiprazole lauroxil is not approved for the treatment of patients with dementia-related psychosis . Commonly used brand name(s) In the U.S. Aristada Available Dosage Forms: Suspension, Extended Release Therapeutic Class: Antipsychotic Uses For aripiprazole lauroxil Aripiprazole lauroxil extended-release injection is used to treat schizophrenia (a mental disorder). It works in the brain to change how certain chemicals affect patients. Aripiprazole is an antipsychotic agent. aripiprazole lauroxil is available only with your doctor's prescription. Before Using aripiprazole lauroxil In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For aripiprazole lauroxil, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to aripiprazole lauroxil or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of aripiprazole lauroxil injection in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies have not been performed on the relationship of age to the effects of aripiprazole lauroxil in the geriatric population. Safety and efficacy have not been established. aripiprazole lauroxil should not be used to treat behavioral problems in elderly patients who have dementia or Alzheimer disease. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving aripiprazole lauroxil, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using aripiprazole lauroxil with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Amifampridine Amisulpride Bepridil Cisapride Dronedarone Mesoridazine Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine Thioridazine Ziprasidone Using aripiprazole lauroxil with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Alfuzosin Amiodarone Amitriptyline Anagrelide Apomorphine Arsenic Trioxide Asenapine Astemizole Azithromycin Bedaquiline Buserelin Chloroquine Chlorpromazine Ciprofloxacin Citalopram Clarithromycin Clomipramine Clozapine Crizotinib Cyclobenzaprine Dabrafenib Dasatinib Degarelix Delamanid Desipramine Deslorelin Disopyramide Dofetilide Dolasetron Domperidone Donepezil Doxepin Droperidol Ebastine Efavirenz Eribulin Erythromycin Escitalopram Famotidine Felbamate Fingolimod Flecainide Fluoxetine Formoterol Foscarnet Galantamine Gatifloxacin Gemifloxacin Gonadorelin Goserelin Granisetron Halofantrine Haloperidol Histrelin Hydroquinidine Hydroxychloroquine Hydroxyzine Ibutilide Iloperidone Imipramine Itraconazole Ivabradine Lapatinib Leuprolide Levofloxacin Lumefantrine Mefloquine Methadone Methotrimeprazine Metronidazole Mifepristone Mizolastine Moricizine Moxifloxacin Nafarelin Nelfinavir Nilotinib Norfloxacin Octreotide Ofloxacin Olanzapine Ondansetron Paliperidone Panobinostat Papaverine Paroxetine Pasireotide Pazopanib Pentamidine Perphenazine Pimavanserin Pipamperone Pitolisant Probucol Procainamide Prochlorperazine Promethazine Propafenone Protriptyline Quetiapine Quinidine Quinine Ranolazine Ribociclib Risperidone Ritonavir Sertindole Sevoflurane Sodium Phosphate Sodium Phosphate, Dibasic Sodium Phosphate, Monobasic Solifenacin Sorafenib Sotalol Sulpiride Sultopride Sunitinib Tacrolimus Tamoxifen Telaprevir Telavancin Telithromycin Tetrabenazine Tizanidine Tolterodine Toremifene Trazodone Trimipramine Triptorelin Vandetanib Vardenafil Vemurafenib Venlafaxine Vilanterol Vinflunine Voriconazole Vorinostat Zotepine Zuclopenthixol Using aripiprazole lauroxil with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Boceprevir Bupropion Cobicistat Conivaptan Enzalutamide Idelalisib Indinavir Ketoconazole Lopinavir Lumacaftor Mitotane Nefazodone Phenytoin Posaconazole Rifampin St John's Wort Terbinafine Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of aripiprazole lauroxil. Make sure you tell your doctor if you have any other medical problems, especially: Blood vessel disease or Dehydration or Heart attack or stroke, history of or Heart disease or Heart failure, history of or Heart rhythm problems or Hypotension (low blood pressure) or Hypovolemia (decrease in the volume of blood) or Ischemic heart disease, history of or Trouble with swallowing Use with caution. May cause side effects to become worse. Depression or Diabetes, or family history of or Dyslipidemia (high cholesterol or fats in the blood) or Hyperglycemia (high blood sugar) or Neuroleptic malignant syndrome (NMS), history of or Neutropenia (low white blood cells) or Seizures, history of Use with caution. May make these conditions worse. Proper Use of aripiprazole lauroxil A nurse or other trained health professional will give you aripiprazole lauroxil in a hospital or clinic. It will be given as a shot into a muscle. aripiprazole lauroxil comes with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand. Missed Dose aripiprazole lauroxil needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions. Be sure to keep all appointments for the injections. Precautions While Using aripiprazole lauroxil It is very important that your doctor check your progress at regular visits to allow for changes in your dose and help reduce any unwanted effects. Blood and urine tests may be needed to check for unwanted effects. aripiprazole lauroxil may increase risk for stroke in elderly patients with dementia. Tell your doctor right away if you have confusion, difficulty in speaking, slow speech, inability to speak, inability to move the arms, legs, or facial muscles, double vision, or headache while using aripiprazole lauroxil. aripiprazole lauroxil may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor. aripiprazole lauroxil may add to the effects of alcohol and other medicines that make you drowsy or less alert. Some examples of these medicines are antihistamines or medicines for hay fever, allergies, or colds, sedatives, tranquilizers, or sleeping medicines, prescription pain medicines or narcotics, medicines for seizures or barbiturates, muscle relaxants, or anesthetics (medicines that numb), including some dental anesthetics. If you are taking any of these medicines, make sure you tell your doctor before you receive aripiprazole injection . Aripiprazole may cause drowsiness, trouble with thinking, or trouble with controlling movements. Make sure you know how you react to aripiprazole lauroxil before you drive, use machines, or do other jobs that require you to be alert, well-coordinated, or able to think well . Check with your doctor right away if you have any of the following symptoms while using aripiprazole lauroxil: convulsions (seizures), difficulty with breathing, a fast heartbeat, a high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS). aripiprazole lauroxil may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have any of the following symptoms while using aripiprazole lauroxil: lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs. Some people who have used aripiprazole lauroxil had unusual changes in their behavior. Talk with your doctor right away if you start having unusual urges, such as gambling urges, binge or compulsive eating, compulsive shopping, or sexual urges while using aripiprazole lauroxil. Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. Getting up slowly may help. If this problem continues or gets worse, check with your doctor. aripiprazole lauroxil may make it more difficult for your body to cool down. It might reduce how much you sweat. Your body could get too hot if you do not sweat enough. If your body gets too hot, you might feel dizzy, weak, tired, or confused. Avoid places that are very hot. Call your doctor if drinking cool water and moving away from the heat does not cool you down. aripiprazole lauroxil can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. aripiprazole lauroxil may increase your weight. Your doctor may need to check your weight on a regular basis while you are using aripiprazole lauroxil. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines) and herbal or vitamin supplements. aripiprazole lauroxil Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common Difficulty with speaking drooling loss of balance control muscle trembling, jerking, or stiffness restlessness shuffling walk stiffness of the limbs twisting movements of the body uncontrolled movements, especially of the face, neck, and back Less common Blurred vision dizziness fast, pounding, or irregular heartbeat or pulse headache inability to move the eyes increased blinking or spasms of the eyelid nervousness pounding in the ears sticking out the tongue trouble breathing or swallowing unusual facial expressions Rare Convulsions fast heartbeat high fever increased sweating lip smacking or puckering loss of bladder control muscle spasm or jerking of all extremities puffing of the cheeks rapid or worm-like movements of the tongue severe muscle stiffness sudden loss of consciousness tiredness uncontrolled chewing movements uncontrolled movements of the arms and legs unusually pale skin Incidence not known Hives or welts, itching, or skin rash itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs redness of the skin tightness in the chest unusual tiredness or weakness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Acid or sour stomach belching difficulty having a bowel movement (stool) dry mouth fear fever headache heartburn hyperventilation inability to sit still indigestion irritability lightheadedness need to keep moving runny nose shaking sore throat stomach discomfort, upset, or pain trouble sleeping weight gain Less common Accidental injury bloating or swelling of the face, arms, hands, lower legs, or feet body aches or pain congestion coughing difficulty with moving hoarseness increased appetite joint pain muscle aching or cramping muscle pains or stiffness sneezing stuffy nose swollen joints tender, swollen glands in the neck tingling of the hands or feet tremor unusual weight gain or loss voice changes Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Print this page The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved.} Recently Approved Lonhala Magnair Lonhala Magnair (glycopyrrolate) is a long-acting muscarinic antagonist (LAMA) bronchodilator for... 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