always apraclonidine (Ophthalmic route) a-pra-KLON-i-deen Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Iopidine Available Dosage Forms: Solution Therapeutic Class: Antiglaucoma Pharmacologic Class: Alpha-2 Adrenergic Agonist Slideshow Aging Eyes - 8 Common Vision Problems Associated with Aging Uses For apraclonidine Apraclonidine 0.5% eye drops is used to treat glaucoma when the medications you have been using for glaucoma do not reduce your eye pressure enough. Apraclonidine 1% eye drops is used just before and after certain types of eye surgery (argon laser trabeculoplasty, argon laser iridotomy, and Nd:YAG laser posterior capsulotomy). The medicine is used to control or prevent a rise in pressure within the eye (ocular hypertension) that can occur after this type of surgery. Apraclonidine 0.5% and 1% are available only with your doctor's prescription. Before Using apraclonidine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For apraclonidine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to apraclonidine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of apraclonidine eye drops in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of apraclonidine eye drops in the elderly. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of apraclonidine. Make sure you tell your doctor if you have any other medical problems, especially: Heart attack, history of or Heart or blood vessel disease (eg, Raynaud's disease, thromboangiitis obliterans) or High blood pressure or Kidney disease or Stroke, history of or Vasovagal attack (rapid decrease in heart rate and blood pressure that can lead to fainting), history of Use with caution. May make these conditions worse. Proper Use of apraclonidine apraclonidine is available in 2 forms: apraclonidine 0.5% eye drops and apraclonidine 1% eye drops. Ask your doctor or pharmacist if you have any questions. Apraclonidine 0.5% eye drops : Use apraclonidine only as directed. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of too much medicine being absorbed into the body and the chance of side effects. First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye. If you think you did not get the drop of medicine into your eye properly, use another drop. To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed. If your doctor ordered two different eye drops to be used together, wait at least 10 minutes between the times you apply the medicines. This will help to keep the second medicine from washing out the first one. Apraclonidine 1% eye drops : A doctor or other trained health professional will give you apraclonidine. You will receive one drop of apraclonidine in the affected eye 1 hour before surgery, then one drop in the same eye immediately after surgery. Dosing The dose of apraclonidine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of apraclonidine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For ophthalmic solution (eye drops) dosage form: For glaucoma (0.5% apraclonidine): Adults Use one drop in each eye two or three times a day. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of apraclonidine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Apraclonidine 0.5% eye drops may be stored in the refrigerator. Precautions While Using apraclonidine It is very important that your doctor check your progress at regular visits to make sure apraclonidine is working properly and to check for unwanted effects. apraclonidine may cause some people to become dizzy, drowsy, or less alert than they are normally. Make sure you know how you react to apraclonidine before you drive, use machines, or do anything else that could be dangerous if you are not alert . Do not use apraclonidine if you are also taking a MAO inhibitor (MAOI). Apraclonidine 0.5% eye drops may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort. apraclonidine Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: For 0.5% apraclonidine More common Allergic reaction (redness, itching, tearing of the eye) Less common Blurred vision or change in vision chest pain clumsiness or unsteadiness depression dizziness eye discharge, irritation, or pain irregular heartbeat numbness or tingling in the fingers or toes raising of the upper eyelid rash around the eyes redness of the eyelid or inner lining of the eyelid swelling of the eye, eyelid, or inner lining of the eyelid swelling of the face, hands, or feet For 1% apraclonidine Less common Blurred vision diarrhea dry mouth eye redness fainting feeling cold or sleepy irregular heartbeat lightheadedness redness, swelling, or whitening of the eyelids slow heartbeat stomach pain stuff or runny nose swelling of the eyelid trouble sleeping unusual dreams unusual taste in the mouth vomiting watering of eye Get emergency help immediately if any of the following symptoms of overdose occur: For 1% apraclonidine Symptoms of overdose Confusion clumsiness drowsiness low body temperature muscle aches muscle weakness shivering sleepiness slow heartbeat tiredness weak or feeble pulse weight gain Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: For 0.5% apraclonidine More common Dryness of the mouth eye discomfort Less common Change in taste or smell constipation crusting or scales on the eyelid or corner of the eye discoloration of white part of the eye drowsiness or sleepiness dry nose or eyes general feeling of discomfort or illness headache increased sensitivity of the eyes to light muscle aches nausea nervousness paleness of the eye or inner lining of the eyelid runny nose sore throat tiredness or weakness trouble in sleeping For 1% apraclonidine More common Increase in size of the pupil of the eye paleness of the eye or inner lining of the eyelid Less common Runny nose Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. 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Next Side Effects Print this page Add to My Med List More about apraclonidine ophthalmic Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: ophthalmic glaucoma agents Consumer resources Apraclonidine ophthalmic Apraclonidine Other brands: Iopidine Professional resources Apraclonidine Hydrochloride (AHFS Monograph) Apraclonidine (FDA) Apraclonidine (Wolters Kluwer) Related treatment guides Glaucoma Postoperative Increased Intraocular Pressure} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Akorn, Inc. Sandoz Inc. Drug Class Ophthalmic glaucoma agents Related Drugs Glaucoma Combigan , nadolol , pilocarpine ophthalmic , acetazolamide , Diamox , mitomycin ophthalmic , Corgard , methazolamide , physostigmine ophthalmic , carbachol ophthalmic , Diamox Sequels , More... Postoperative Increased Intraocular Pressure Ilevro , Nevanac , nepafenac ophthalmic , Iopidine , More... Apraclonidine ophthalmic Rating No Reviews - Be the first! 8.0 /10 No Reviews - Be the first! 8.0 Rate it! Help and Support Looking for answers? Ask a question or go join the apraclonidine support group to connect with others who have similar interests.} } the jobs
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