land up entecavir (Oral route) en-TEK-a-vir Oral route(Tablet;Solution) Severe acute exacerbations of hepatitis B have been reported upon discontinuation of anti-hepatitis B therapy, including entecavir. Hepatic function should be monitored closely for at least several months in patients who discontinue therapy and reinitiation of anti-hepatitis B therapy may be warranted. Entecavir is not recommended in HIV/HBV co-infected patients not treated with highly active antiretroviral therapy because there is potential for the development of resistance to HIV nucleoside reverse transcriptase inhibitors. Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogue inhibitors . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Baraclude Available Dosage Forms: Solution Tablet Therapeutic Class: Antiviral Chemical Class: Guanosine Nucleoside Analog Slideshow Think Before You Ink: Health Risks Associated With Tattoos Uses For entecavir Entecavir is used to treat liver infection caused by hepatitis B virus. It belongs to the family of medicines called antivirals. Antivirals are used to treat infections that are caused by viruses. entecavir will not cure the hepatitis B virus, but it will keep it from reproducing and causing more liver damage. entecavir is available only with your doctor's prescription. Before Using entecavir In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For entecavir, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to entecavir or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of entecavir in children younger than 2 years of age. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of entecavir in the elderly. However, elderly patients are more likely to have age-related kidney disease, which may require an adjustment in the dose for patients receiving entecavir. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Other Medical Problems The presence of other medical problems may affect the use of entecavir. Make sure you tell your doctor if you have any other medical problems, especially: Kidney disease Use with caution. The effects may be increased because of slower removal of the medicine from the body. Liver disease or Liver transplant, or history of May increase chance for serious side effects. Proper Use of entecavir Take entecavir exactly as directed by your doctor . Do not take it more often, and do not take it for a longer time than your doctor ordered. When your supply of entecavir is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of entecavir. Also, do not stop taking entecavir without checking with your doctor first. Read and follow carefully the patient information leaflet before starting entecavir treatment and each time you refill. Ask your doctor or pharmacist if you have any questions. Take entecavir on an empty stomach (at least 2 hours after a meal and 2 hours before the next meal). Measure the oral liquid correctly using the marked measuring spoon that comes with the package. Rinse the dosing spoon with water after each use. Dosing The dose of entecavir will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of entecavir. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage forms (solution or tablets): For chronic hepatitis B infection: Adults and children 16 years of age and older 0.5 to 1 milligram (mg) or 10 to 20 milliliters (mL) once per day. Children 2 years of age and older weighing more than 30 kilograms (kg) 0.5 to 1 milligram (mg) or 10 to 20 milliliters (mL) once per day. Children 2 years of age and older weighing 10 to 30 kg dose is determined by body weight, usually between 3 to 20 milliliters (mL) once a day. Children younger than 2 years of age Use and dose must be determined by your doctor. Missed Dose If you miss a dose of entecavir, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using entecavir It is very important that your doctor check your or your child's progress at regular visits . This will allow your doctor to see if the medicine is working properly. Blood tests may be needed to check for unwanted effects. It is important to tell your doctor if you become pregnant. Your doctor may want you to join a pregnancy registry for patients taking entecavir. If you have or get HIV (human immunodeficiency virus) infection, be sure to discuss your treatment with your doctor. If you are taking entecavir to treat chronic hepatitis B and are not taking medicines for your HIV at the same time, some HIV treatments that you take in the future may be less likely to work. Your doctor may need you to get an HIV test before you start taking entecavir and anytime after that when there is a chance you were exposed to HIV. entecavir will not help your HIV infection. Two rare but serious reactions to entecavir are lactic acidosis (too much acid in the blood) and liver toxicity, which includes an enlarged liver. These are more common if you are female, very overweight (obese), or have been taking anti-HIV medicines for a long time. Call your doctor right away if you or your child feel tired, weak, dizzy, or nauseated, if you vomit or have stomach pain, dark urine, light-colored stools, unusual muscle pains, trouble with breathing, or if your skin or eyes turn yellow. Liver disease may become worse if treatment with entecavir is stopped. Do not stop taking entecavir unless your doctor tells you to stop. Treatment with entecavir has not been shown to decrease the chance of giving hepatitis B virus infection to other people through sexual contact or blood contamination. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. entecavir Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Incidence not known Abdominal or stomach discomfort cough decreased appetite diarrhea difficulty with swallowing dizziness fast heartbeat fast, shallow breathing general feeling of discomfort hives, itching, or rash muscle pain or cramping nausea puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue right upper abdominal or stomach pain and fullness sleepiness tightness in the chest unusual tiredness or weakness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Acid or sour stomach belching headache heartburn indigestion stomach discomfort, upset, or pain Rare Trouble sleeping Unusual drowsiness Incidence not known Hair loss thinning of the hair Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about entecavir Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 1 Review Add your own review/rating Drug class: nucleoside reverse transcriptase inhibitors (NRTIs) Consumer resources Entecavir Entecavir Tablets Entecavir Oral Solution Other brands: Baraclude Professional resources Entecavir (AHFS Monograph) Entecavir (FDA) Entecavir (Wolters Kluwer) Related treatment guides Hepatitis B} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Amneal Pharmaceuticals LLC Par Pharmaceutical, Inc. Teva Pharmaceuticals USA, Inc. Zydus Pharmaceuticals (USA) Inc. Aurobindo Pharma Limited Camber Pharmaceuticals, Inc. AvKare, Inc. More... Drug Class Nucleoside reverse transcriptase inhibitors (NRTIs) Related Drugs Hepatitis B Viread , lamivudine , tenofovir , Baraclude , Epivir , Vemlidy , Pegasys , Intron A , adefovir , Hepsera , PegIntron , interferon alfa-2b , Epivir-HBV , Tyzeka , peginterferon alfa-2b , telbivudine , More... Entecavir Rating 1 User Review 10 /10 1 User Review 10 Rate it! Entecavir Images Entecavir systemic 0.5 mg (TEVA 5786) View all images Related Questions & Answers Baraclude - would like to hear from anyone who has been on this for more than 5 years? How much amount of super disintegrant can be used in formulation of 1mg entecavir tablets? Read more questions} } and you are going
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