geared toward Enstilar (Topical application) Generic Name: betamethasone and calcipotriene (Topical application route) bay-ta-METH-a-sone dye-PROE-pee-oh-nate, kal-si-poe-TRYE-een Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Enstilar Taclonex Taclonex Scalp Available Dosage Forms: Ointment Foam Suspension Therapeutic Class: Antipsoriatic Pharmacologic Class: Betamethasone Slideshow Psoriasis: Treatment Options to Manage Your Symptoms and Skin Uses For Enstilar Betamethasone and calcipotriene combination is used on the skin and scalp to treat plaque psoriasis. Betamethasone is a corticosteroid (cortisone-like medicine or steroid). It helps relieve redness, pain, itching, swelling, or other discomfort caused by certain skin problems. Calcipotriene is a form of Vitamin D. It works by changing how the skin cells are produced in the areas affected by psoriasis. This medicine is available only with your doctor's prescription. Before Using Enstilar In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of betamethasone and calcipotriene topical ointment and suspension in children younger than 12 years of age. Safety and efficacy have not been established. Appropriate studies have not been performed on the relationship of age to the effects of betamethasone and calcipotriene topical foam in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of betamethasone and calcipotriene combination in the elderly. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Desmopressin Rotavirus Vaccine, Live Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aceclofenac Acemetacin Aldesleukin Amtolmetin Guacil Bemiparin Bromfenac Bufexamac Bupropion Celecoxib Choline Salicylate Clonixin Dexibuprofen Dexketoprofen Diclofenac Diflunisal Dipyrone Droxicam Etodolac Etofenamate Etoricoxib Felbinac Fenoprofen Fepradinol Feprazone Floctafenine Flufenamic Acid Flurbiprofen Ibuprofen Indomethacin Ketoprofen Ketorolac Lornoxicam Loxoprofen Lumiracoxib Meclofenamate Mefenamic Acid Meloxicam Morniflumate Nabumetone Nadroparin Naproxen Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Oxaprozin Oxyphenbutazone Parecoxib Phenylbutazone Piketoprofen Piroxicam Pixantrone Pranoprofen Proglumetacin Propyphenazone Proquazone Rofecoxib Salicylic Acid Salsalate Sodium Salicylate Sulindac Tenoxicam Tiaprofenic Acid Tolfenamic Acid Tolmetin Valdecoxib Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Alcuronium Aspirin Atracurium Desogestrel Dienogest Drospirenone Estradiol Cypionate Estradiol Valerate Ethinyl Estradiol Ethynodiol Diacetate Etonogestrel Fosphenytoin Gallamine Hexafluorenium Levonorgestrel Licorice Medroxyprogesterone Acetate Mestranol Metocurine Norelgestromin Norethindrone Norgestimate Norgestrel Phenobarbital Phenytoin Primidone Rifampin Rifapentine Saiboku-To Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Atrophy (thin skin) at the site to be treated or Cushing's syndrome (adrenal gland disorder) or Diabetes or Hyperglycemia (high blood sugar) or Intracranial hypertension (increased pressure in the head) Use with caution. May make these conditions worse. Erythrodermic (redness), exfoliative (peeling), or pustular (with pus) psoriasis or Hypercalcemia (high calcium in the blood) or Hypercalciuria (high calcium in the urine) or Kidney disease, severe or Liver disease, severe Use has not been studied in patients with these conditions. . Infection of the skin or scalp at or near the place of application or Large sores, broken skin, or severe skin injury at the place of application or Liver failure The chance of side effects may be increased. Proper Use of betamethasone and calcipotriene This section provides information on the proper use of a number of products that contain betamethasone and calcipotriene. It may not be specific to Enstilar. Please read with care. It is very important that you use this medicine only as directed by your doctor . Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation. This medicine should only be used on the skin or scalp only . Do not get it in your eyes, nose, mouth, vagina, or apply it on your face, under your arms, or on your groin area. Do not use it on skin or scalp areas that have cuts or scrapes. If it does get on these areas, rinse it off right away with water. This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions. To help clear up your skin or scalp problem completely, it is very important that you keep using this medicine for the full time of treatment . Do not miss any doses. This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other skin conditions, especially if you think that a skin infection may be present . This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns. The treated areas should not be bandaged or covered after the medicine is applied. To use the foam : Wash your hands before and after using this medicine. Shake the foam can before using the medicine. Apply the medicine to the affected areas of the skin and rub it in gently. Use this medicine within 6 months after opening. This medicine can catch on fire. Do not use it near heat, an open flame, or while smoking. To use the ointment : Wash your hands with soap and water before and after using this medicine. Apply a thin layer to the affected areas of the skin and rub it in gently. Do not use the ointment for more than 8 weeks unless your doctor has told you to. To use the topical suspension : Wash your hands with soap and water before and after using this medicine. Shake the bottle before using the medicine. Part your hair so you can see the patches on your scalp. Apply enough medicine to the affected areas on your scalp and rub it in gently. Do not wash your hair or take a bath or shower right after applying this medicine. Do not apply this medicine in the 12 hours before or after using any hair chemical treatments. Talk with your doctor first about it. Do not use the topical suspension for more than 8 weeks unless your doctor has told you to. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For topical dosage form (foam): For plaque psoriasis: Adults Apply to the affected area of the skin once a day for up to 4 weeks or until the area is cleared or as determined by your doctor. Do not use more than 60 grams every 4 days. Children Use and dose must be determined by your doctor. For topical dosage form (ointment): For plaque psoriasis: Adults Apply to the affected area of the skin once a day for up to 4 weeks or until the area is cleared or as determined by your doctor. Do not use more than 100 grams per week. Children 12 to 17 years of age Apply to the affected area of the skin once a day for up to 4 weeks or until the area is cleared or as determined by your doctor. Do not use more than 60 grams per week. Children younger than 12 years of age Use and dose must be determined by your doctor. For topical dosage form (suspension): For plaque psoriasis of the body: Adults Apply to the affected area of the skin once a day for up to 8 weeks or until the area is cleared or as determined by your doctor. Do not use more than 100 grams per week. Children Use and dose must be determined by your doctor. For plaque psoriasis of the scalp: Adults Apply to the affected area on the scalp once a day for up to 8 weeks or until the area is cleared or as determined by your doctor. Do not use more than 100 grams per week. Children 12 to 17 years of age Apply to the affected area on the scalp once a day for up to 8 weeks or until the area is cleared or as determined by your doctor. Do not use more than 60 grams per week. Children younger than 12 years of age Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Keep the bottle of topical suspension in the carton when not in use. Use it within 6 months after it has been opened. Store the foam can at room temperature, away from heat and direct light. Do not keep this medicine inside a car where it could be exposed to extreme heat. Do not poke holes in the canister or throw it into a fire, even if the canister is empty. Precautions While Using Enstilar It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood, urine, and other tests may be needed to check for unwanted effects. If your psoriasis does not improve within a few weeks or become worse, check with your doctor. Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor if you have more than one of these symptoms while you are using this medicine: darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. This medicine may cause too much calcium to build up in your body. Talk to your doctor if you have more than one of these symptoms while you are using this medicine: abdominal or stomach pain, confusion, constipation, depression, dry mouth, headache, incoherent speech, increased urination, loss of appetite, a metallic taste, muscle weakness, nausea, thirst, unusual tiredness, vomiting, or weight loss. Check with your doctor right away if you have a blistering, burning, crusting, dryness, flaking, itching, scaling, severe redness, soreness, or swelling of the skin. Make sure your doctor knows if you are also having ultraviolet (UV) light treatments (phototherapy) for your psoriasis before using this medicine. This medicine may make your skin more sensitive to sunlight. Use a sunscreen and wear protective clothing when you are outdoors. Avoid sunlamps and tanning beds. Do not use cosmetics or other skin care products on the treated areas. Enstilar Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Burning, itching, and pain in hairy areas burning sensation of the skin flushing or redness of the skin itching skin pus at the root of the hair red, scaling, or crusted skin scaly rash skin irritation thinning of the skin with easy bruising unusually warm skin Rare Body aches or pain chills cough darkening of the skin diarrhea difficulty with breathing ear congestion fever general feeling of discomfort or illness headache joint pain lightening of normal skin color lightening of the treated areas of dark skin loss of appetite loss of voice muscle aches and pains nasal congestion nausea raised, dark red, or wart-like spots on skin red, sore eyes runny nose shivering sneezing sore throat spots on your skin that look like a blister or pimple sweating trouble sleeping unusual tiredness or weakness vomiting worsening of the psoriasis Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Bruising large, flat, blue, or purplish patches in the skin pain Rare Blemishes on the skin pimples Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Enstilar (betamethasone / calcipotriene topical) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 4 Reviews Add your own review/rating Drug class: topical antipsoriatics Consumer resources Enstilar topical Enstilar Other brands: Taclonex , Taclonex Scalp Professional resources Enstilar (FDA) Related treatment guides Plaque Psoriasis Psoriasis} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturer LEO Pharma Inc. Drug Class Topical antipsoriatics Related Drugs Plaque Psoriasis Humira , dexamethasone , methylprednisolone , betamethasone topical , Enbrel , Remicade , Otezla , adalimumab , calcipotriene topical , infliximab , etanercept , Cosentyx , More... Psoriasis Humira , methotrexate , cyclosporine , Remicade , adalimumab , infliximab , Stelara , Trexall , Rasuvo , acitretin , Neoral , More... Enstilar Rating 4 User Reviews 5.5 /10 4 User Reviews 5.5 Rate it! Help and Support Looking for answers? Ask a question or go join the Enstilar support group to connect with others who have similar interests.} } demanding
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