barely enough enalaprilat (Intravenous route) en-AL-a-pril-at Intravenous route(Solution) When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. When pregnancy is detected, enalaprilat injection should be discontinued as soon as possible . Overview Side Effects Professional Interactions Pregnancy More User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Vasotec I.V. Available Dosage Forms: Solution Therapeutic Class: Antihypertensive Pharmacologic Class: ACE Inhibitor Slideshow Amyotrophic Lateral Sclerosis (ALS): Evolving Science For a Fatal Disease Uses For enalaprilat Enalaprilat injection is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled . Enalaprilat works by blocking an enzyme in the body that is necessary to produce a substance that causes blood vessels to tighten. As a result, the blood vessels relax. This lowers blood pressure and increases the supply of blood and oxygen to the heart . enalaprilat is available only with your doctor's prescription . Before Using enalaprilat In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For enalaprilat, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to enalaprilat or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of enalaprilat in the pediatric population. Safety and efficacy have not been established . Geriatric No information is available on the relationship of age to the effects of enalaprilat in geriatric patients. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment of dose in patients receiving enalaprilat . Pregnancy Pregnancy Category Explanation 1st Trimester C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. 2nd Trimester D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. 3rd Trimester D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. Breast Feeding Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving enalaprilat, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using enalaprilat with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Aliskiren Sacubitril Using enalaprilat with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Allopurinol Alteplase, Recombinant Amiloride Azathioprine Azilsartan Azilsartan Medoxomil Candesartan Cilexetil Canrenoate Eplerenone Eprosartan Everolimus Interferon Alfa-2a Irbesartan Lithium Losartan Mercaptopurine Olmesartan Medoxomil Oxypurinol Potassium Sirolimus Spironolactone Telmisartan Triamterene Trimethoprim Valsartan Using enalaprilat with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aceclofenac Acemetacin Amtolmetin Guacil Aspirin Azosemide Bromfenac Bufexamac Bumetanide Bupivacaine Bupivacaine Liposome Capsaicin Celecoxib Choline Salicylate Clomipramine Clonixin Dexibuprofen Dexketoprofen Diclofenac Diflunisal Dipyrone Droxicam Ethacrynic Acid Etodolac Etofenamate Etoricoxib Felbinac Fenoprofen Fepradinol Feprazone Floctafenine Flufenamic Acid Flurbiprofen Furosemide Gold Sodium Thiomalate Ibuprofen Indomethacin Ketoprofen Ketorolac Lornoxicam Loxoprofen Lumiracoxib Meclofenamate Mefenamic Acid Meloxicam Morniflumate Nabumetone Naproxen Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Oxaprozin Oxyphenbutazone Parecoxib Phenylbutazone Piketoprofen Piretanide Piroxicam Proglumetacin Propionic Acid Propyphenazone Proquazone Rifampin Rofecoxib Salicylic Acid Salsalate Sodium Salicylate Sulindac Tenoxicam Tiaprofenic Acid Tolfenamic Acid Tolmetin Torsemide Valdecoxib Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of enalaprilat. Make sure you tell your doctor if you have any other medical problems, especially: Angioedema, history of May increase the risk of this condition occurring again . Dehydration or Diarrhea or Heart failure or Hyponatremia (low sodium in the blood) or Kidney disease These conditions may cause the blood pressure to fall too low with enalaprilat . Proper Use of enalaprilat In addition to the use of enalaprilat, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Remember that enalaprilat will not cure your high blood pressure but it does help control it. Therefore, you must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life . If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. Precautions While Using enalaprilat It is very important that your doctor check your progress at regular visits to make sure enalaprilat is working properly and to check for unwanted effects . Stop using enalaprilat and call your doctor right away if you have swelling of the face, arms, legs, eyes, lips, or tongue, or problems with swallowing or breathing. These are symptoms of a condition called angioedema . You may experience lightheadedness during the first few days with enalaprilat. If this becomes severe and you faint, talk to your doctor right away . Tell your doctor immediately if you have any signs of infection such as chills, sore throat, or fever. These may be symptoms of an immune system condition called neutropenia . Using enalaprilat while you are pregnant can harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away . Check with your doctor right away if you have symptoms of jaundice (yellow skin or eyes) because these may be signs of a serious liver condition . enalaprilat may increase the amount of potassium in your blood. Do not use salt substitutes containing potassium without first checking with your doctor . Make sure any doctor or dentist who treats you knows that you are using enalaprilat. You may need to stop using enalaprilat several days before having surgery or medical tests . enalaprilat Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: Less common Blurred vision confusion dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly sweating unusual tiredness or weakness Rare Chest pain or discomfort nausea pain or discomfort in arms, jaw, back or neck shortness of breath vomiting Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Headache Rare Difficulty having a bowel movement (stool) dizziness fever rash Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about enalaprilat Side Effects During Pregnancy Drug Interactions Support Group Pricing & Coupons 0 Reviews Add your own review/rating Drug class: Angiotensin Converting Enzyme Inhibitors Consumer resources Enalaprilat Professional resources Enalaprilat (FDA)} Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Pfizer Inc. 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