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keep fit exercise [31%),:<1% (Limited to important or life-threatening): Application site pain, contact dermatitis, hypersensitivity reaction, local skin exfoliation Warnings/Precautions Concerns related to adverse effects: Bleaching effects: Benzoyl peroxide may bleach hair, colored fabric, or carpeting. Diarrhea: Systemic absorption may occur after topical use of clindamycin. C. difficile -associated diarrhea (CDAD) and pseudomembranous colitis have been reported and have been observed> 2 months postantibiotic treatment. Use of parenteral and systemic clindamycin has resulted in severe colitis (including fatalities). Discontinue drug if significant diarrhea, abdominal cramps, or passage of blood and mucus occurs. Hypersensitivity: Anaphylaxis and allergic reactions have been reported, may occur within minutes to a day or longer, and differ from local skin irritation. Skin irritation: Use concomitant topical acne therapy with caution; cumulative irritancy may occur, especially with the use of peeling, desquamating, or abrasive agents. Concurrent drug therapy issues: Drug-drug interactions: Potentially significant interactions may exist, requiring dose or frequency adjustment, additional monitoring, and/or selection of alternative therapy. Consult drug interactions database for more detailed information. Sulfone products: Concomitant use of benzoyl peroxide with sulfone products (eg, dapsone, sulfacetamide) may cause temporary discoloration (yellow/orange) of facial hair and skin. Application of products at separate times during the day or washing off benzoyl peroxide prior to application of other products may avoid skin discoloration (Dubina 2009). Other warnings/precautions: Appropriate use: For external use only; not for vaginal or ophthalmic use. Avoid contact with mucous membranes. Inform patients to use skin protection and minimize prolonged exposure to sun and avoid tanning beds or sun lamps. Pregnancy Risk Factor C Pregnancy Considerations Animal reproduction studies have not been conducted with this combination. Refer to individual monographs. Patient Education Discuss specific use of drug and side effects with patient as it relates to treatment. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?) Patient may experience dry skin or itching. Have patient report immediately to prescriber severe skin irritation or signs of Clostridium difficile ( C. diff )-associated diarrhea (abdominal pain or cramps, severe diarrhea or watery stools, or bloody stools) (HCAHPS). Educate patient about signs of a significant reaction (eg, wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat). Note: This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions. Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for healthcare professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience and judgment in diagnosing, treating and advising patients. Next Interactions Print this page Add to My Med List More about benzoyl peroxide/clindamycin topical Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En EspaƱol 374 Reviews Add your own review/rating Drug class: topical acne agents Consumer resources Benzoyl peroxide and clindamycin topical ... +5 more Professional resources Clindamycin Phosphate and Benzoyl Peroxide (FDA) Other brands: Benzaclin , Duac , Onexton , Acanya , Neuac Related treatment guides Acne ] Antibiotics 101 Everything you need to know about antibiotics: List of Common Antibiotics & Types Antibiotics & Drinking Alcohol - Is it Safe? Antibiotics For UTI - What Are My Options? Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Benzoyl peroxide / clindamycin topical Rating 374 User Reviews 8.0 /10 374 User Reviews 8.0 Rate it! Manufacturers Mylan Pharmaceuticals Inc. Perrigo Company Prasco Laboratories Drug Class Topical acne agents Related Drugs topical acne agents clindamycin topical , erythromycin topical , tretinoin topical , tetracycline topical , dapsone topical , Finacea Acne doxycycline , clindamycin topical , erythromycin topical , minocycline , tretinoin topical , tetracycline topical , dapsone topical , Accutane , Vibramycin , Retin-A , isotretinoin , Minocin , Ortho Tri-Cyclen , Yasmin , Monodox , adapalene topical , Yaz , TriNessa , Epiduo , Claravis , Benzaclin , Tazorac , Differin , Adoxa , More... the goods


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