to picking Fareston (Oral) Generic Name: toremifene (Oral route) tore-EM-i-feen SIT-rate Oral route(Tablet) Toremifene prolongs the QTc interval in a dose- and concentration-related manner and may cause a type of ventricular tachycardia called Torsade de pointes. This could result in syncope, seizures, and/or death. Toremifene should not be prescribed to patients with congenital/acquired QT prolongation, uncorrected hypokalemia, or uncorrected hypomagnesemia. Drugs known to prolong the QT interval and strong CYP3A4 inhibitors should be avoided . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Fareston Available Dosage Forms: Tablet Therapeutic Class: Antiestrogen Slideshow Breast Cancer: Your Questions Answered Uses For Fareston Toremifene is used to treat metastatic breast cancer (cancer that has spread) that is hormone-receptor positive in women who have already stopped menstruating (postmenopausal). Many of the breast cancer tumors will grow when estrogen is available in the body. This medicine blocks the effects of the estrogen hormone. As a result, the amount of estrogen that the tumor is exposed to is reduced, which will limit the growth of the tumor. This medicine is available only with your doctor's prescription. Before Using Fareston In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Toremifene is not indicated for use in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of toremifene in the elderly. However, elderly patients are more likely to have age-related liver problems, which may require caution and an adjustment in the dose for patients receiving toremifene. Pregnancy Pregnancy Category Explanation All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Amifampridine Amisulpride Bepridil Cisapride Dronedarone Fluconazole Ketoconazole Mesoridazine Nelfinavir Pimozide Piperaquine Posaconazole Saquinavir Sparfloxacin Terfenadine Thioridazine Ziprasidone Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Alfuzosin Amiodarone Amitriptyline Amoxapine Anagrelide Apomorphine Aripiprazole Aripiprazole Lauroxil Arsenic Trioxide Asenapine Astemizole Atazanavir Azithromycin Buserelin Ceritinib Chloroquine Chlorpromazine Ciprofloxacin Citalopram Clarithromycin Clomipramine Clozapine Cobicistat Crizotinib Dabrafenib Dasatinib Degarelix Delamanid Desipramine Deslorelin Deutetrabenazine Disopyramide Dofetilide Dolasetron Domperidone Donepezil Droperidol Efavirenz Erythromycin Escitalopram Fingolimod Flecainide Fluoxetine Foscarnet Gatifloxacin Gemifloxacin Gonadorelin Goserelin Granisetron Halofantrine Haloperidol Histrelin Hydroxychloroquine Hydroxyzine Ibutilide Idelalisib Iloperidone Imipramine Indinavir Itraconazole Ivabradine Lapatinib Leuprolide Levofloxacin Lopinavir Lumefantrine Mefloquine Methadone Metronidazole Mifepristone Moxifloxacin Nafarelin Nefazodone Nilotinib Norfloxacin Nortriptyline Octreotide Ofloxacin Ondansetron Paliperidone Panobinostat Pasireotide Pazopanib Pimavanserin Pitolisant Procainamide Prochlorperazine Promethazine Propafenone Protriptyline Quetiapine Quinidine Quinine Ranolazine Ribociclib Ritonavir Salmeterol Sevoflurane Sodium Phosphate Sorafenib Sotalol Sugammadex Sulpiride Sunitinib Tacrolimus Telavancin Telithromycin Tetrabenazine Trazodone Trifluoperazine Trimipramine Triptorelin Vandetanib Vardenafil Vemurafenib Venlafaxine Vinflunine Voriconazole Zuclopenthixol Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Grapefruit Juice Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Blood clots, or history of Use is usually not recommended in patients with this condition. Bone problems (eg, bone cancer) or Congestive heart failure or Heart rhythm problems (eg, QT prolongation) or Leukopenia (low white blood cells in the blood) or Thrombocytopenia (low platelets in the blood) Use with caution. May make these conditions worse. Heart rhythm problems (eg, congenital or acquired long QT syndrome) or Hypokalemia (low potassium in the blood), uncorrected or Hypomagnesemia (low magnesium in the blood), uncorrected Should not be used in patients with these conditions. Liver disease (eg, cirrhosis, fibrosis) Use with caution. The effects may be increased because of slower removal of the medicine from the body. Unusual growth of the lining of the uterus (womb) Long-term use of toremifene is usually not recommended. Proper Use of Fareston Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment. Use this medicine only as directed by your doctor . Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For breast cancer: Adults 60 milligrams (mg) once a day. Children Use is not recommended. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Fareston It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects. It is important for women to have regular gynecologic check-ups while taking this medicine. It is unlikely that a postmenopausal woman may become pregnant. But, using this medicine while you are pregnant could harm your unborn baby. If you are a woman who can bear children, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away. Contact your doctor right away if you have any changes to your heart rhythm. You might feel dizzy or faint, or you might have a fast, pounding, or uneven heartbeat. Make sure your doctor knows if you had a heart rhythm problem, such as QT prolongation. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem. Hypercalcemia (high calcium in the blood) and tumor flare (increased size of a tumor) are more likely to occur in patients with bone problems who are taking this medicine. Check with your doctor right away if you have stomach pain, confusion, constipation, depression, dry mouth, increased urination, loss of appetite, metallic taste, muscle weakness, pain and swelling in the bones and muscles surrounding a tumor, thirst, unusual tiredness, or weight loss. This medicine may increase your risk of having uterus problems, including endometrial cancer. Talk with your doctor if you have concerns about this. Toremifene can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding: If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Check with your doctor immediately if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin. Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done. Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime. Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters. Avoid contact sports or other situations where bruising or injury could occur. This medicine may cause you to have bleeding from the vagina, especially when you first start using it. If the bleeding continues or is bothersome, check with your doctor right away. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements. Fareston Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Anxiety arm, back, or jaw pain blurred vision change in how much and how often you urinate change in vaginal discharge changes in skin color changes in vision changes in weight chest pain, discomfort, tightness, or heaviness confusion constipation cough depression dilated neck veins dizziness, lightheadedness dry mouth fainting fast, slow, or irregular heartbeat inability to speak, incoherent speech irregular breathing loss of appetite metallic taste in the tongue muscle weakness nausea pain or discomfort in the arms, jaw, back, or neck pain or feeling of pressure in the pelvis pain, tenderness, or swelling of the foot or leg seizures severe or sudden headache stomach pain sweating swelling of the face, fingers, feet, or lower legs temporary blindness tenderness, pain, swelling, warmth, skin discoloration, prominent superficial veins over the affected area thirst troubled breathing unusual tiredness or weakness vaginal bleeding vomiting weakness in the arm and or leg on one side of the body, sudden and severe Incidence not known Black, tarry stools bleeding gums blood in the urine or stools chills clay-colored stools dark urine fever itching painful or difficult urination pinpoint red spots on the skin rash sore throat sores, ulcers, or white spots on the lips or in the mouth swollen glands unpleasant breath odor unusual bleeding or bruising vomiting of blood yellow eyes or skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Blindness decreased vision dry eyes feeling of warmth redness of the face, neck, arms, and occasionally, the upper chest sudden sweating sweating Less common Bone pain changes in vision double vision eye pain tearing Incidence not known Blistering, crusting, irritation, itching, or reddening of the skin cracked, dry, or scaly skin depression difficulty having a bowel movement feeling of constant movement of self or surroundings feeling unusually cold hair loss lack or loss of strength partial or slight paralysis sensation of spinning shakiness in the legs, arms, hands, or feet thinning of the hair Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. 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Next Side Effects Print this page Add to My Med List More about Fareston (toremifene) Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: hormones/antineoplastics Consumer resources Fareston Professional resources Fareston (AHFS Monograph) Fareston (FDA) Related treatment guides Breast Cancer Breast Cancer, Metastatic} Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug 10 + years Approval History FDA approved 1997 WADA Class Anti-Doping Classification Drug Class Hormones / antineoplastics Selective estrogen receptor modulators Related Drugs Breast Cancer methotrexate , anastrozole , tamoxifen , letrozole , Arimidex , Femara , exemestane , fluorouracil , Xeloda , Taxol , capecitabine , Aromasin , More... Breast Cancer, Metastatic anastrozole , tamoxifen , letrozole , Arimidex , Femara , Xeloda , Taxol , capecitabine , Ibrance , Herceptin , Faslodex , Taxotere , More... Fareston Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Fareston Images Fareston 60 mg (TO 60 ) View larger images Related Questions & Answers What drug company makes this drug Fareston and how can I get it I have 660 a month to live on? Read more questions} } new version
accredited Fareston (Oral) from time to time
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