it'll romiplostim Generic Name: romiplostim (ROM i PLOS tim) Brand Name: Nplate Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A What is romiplostim? Romiplostim is a man-made form of a protein that increases production of platelets (blood-clotting cells) in your body. Romiplostim is used to prevent bleeding episodes in people with chronic immune thrombocytopenic purpura (ITP), a bleeding condition caused by a lack of platelets in the blood. Romiplostim is usually given after other medications have been tried without successful treatment of symptoms. Romiplostim is not a cure for ITP and it will not make your platelet counts normal if you have this condition. Romiplostim may also be used for purposes not listed in this medication guide. Slideshow Diabetic Nerve Pain: Symptoms And Treatment What is the most important information I should know about romiplostim? Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. What should I discuss with my health care provider before receiving romiplostim? You should not use romiplostim if you are allergic to it. Using romiplostim may increase your risk of developing blood cancers, especially if you have a myelodysplastic syndrome (bone marrow failure disorder, sometimes called "preleukemia"). Talk with your doctor if you have concerns about this risk. To make sure romiplostim is safe for you, tell your doctor if you have: blood or bone marrow cancer such as leukemia, or myelodysplastic syndrome; liver disease; or a history of bleeding problems or a blood clot. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of romiplostim on the baby. It is not known whether romiplostim passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding. How is romiplostim given? Romiplostim is injected under the skin, usually once per week. A healthcare provider will give you this injection. While using romiplostim, you will need frequent blood tests. Using romiplostim long-term can cause harmful effects on your bone marrow that may result in serious blood cell disorders. To be sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. It may take up to 4 weeks of before romiplostim is completely effective in preventing bleeding episodes. For best results, keep receiving the medication as directed. Talk with your doctor if you have any bruising or bleeding episodes after 4 weeks of treatment. After you stop using romiplostim, your risk of bleeding may be even higher than it was before you started treatment. Be extra careful to avoid cuts or injury for at least 2 weeks after you stop using romiplostim. Your blood will need to be tested weekly during this time. What happens if I miss a dose? Call your doctor for instructions if you miss an appointment for your romiplostim injection. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while receiving romiplostim? Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth. Romiplostim side effects Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance; signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or signs of a blood clot in your leg--pain, swelling, warmth, or redness in one or both legs. Common side effects may include: headache; dizziness; muscle or joint pain; pain in your arms, legs, or shoulder; numbness or tingly feeling; sleep problems (insomnia); or stomach pain or indigestion. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) Romiplostim dosing information Usual Adult Dose for Idiopathic (Immune) Thrombocytopenic Purpura: Initial dose: 1 mcg/kg subcutaneous injection once a week based on actual body weight Maintenance dose: Use the lowest dose to achieve and maintain a platelet count of 50 x 10(9)/L or greater as needed to reduce bleeding risk. Maximum dose: 10 mcg/kg/week Comments: In clinical studies, most patients who responded to this drug achieved and maintained platelet counts of 50 x 10(9)/L or greater with a median dose of 2 mcg/kg. Use: Treatment of thrombocytopenia in patients with chronic immune thrombocytopenia (ITP) who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy; use only in patients with ITP whose degree of thrombocytopenia and clinical condition increases the risk for bleeding. What other drugs will affect romiplostim? Other drugs may interact with romiplostim, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using. Next Side Effects Print this page Add to My Med List More about romiplostim Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 2 Reviews Add your own review/rating Drug class: platelet-stimulating agents Consumer resources Romiplostim Romiplostim Subcutaneous (Advanced Reading) Other brands: Nplate Professional resources Romiplostim (AHFS Monograph) RomiPLOStim (Wolters Kluwer) Related treatment guides Idiopathic Thrombocytopenic Purpura Where can I get more information? Your doctor or pharmacist can provide more information about romiplostim. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 5.01. Date modified: December 03, 2017 Last reviewed: June 08, 2017 Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Platelet-stimulating agents Related Drugs Idiopathic Thrombocytopenic Purpura prednisone , triamcinolone , dexamethasone , Decadron , Deltasone , cortisone , Promacta , Kenalog-40 , Gammagard , RhoGAM , Gamunex , Privigen , Sterapred , eltrombopag , Nplate , Octagam , Dexasone , Intron A , Gamunex-C , MICRhoGAM , Carimune , Prednicot , Dexpak Taperpak , Flebogamma , More... Romiplostim Rating 2 User Reviews 8.7 /10 2 User Reviews 8.7 Rate it! Related Questions & Answers Has anyone taken the maximum dose of Romiplostim ? Will it work for me? Romiplostim - I took one injection and my platelets went up BUT I got a blood clot in my leg, both? Read more questions tune
bump into romiplostim hectic
EmoticonEmoticon