capacity [0.5:<0.38%; however, the RID varied with the time postpartum and the milk protein content. The RID was highest in the colostral phase when the milk protein content was the highest (RID 0.6%). The estimated mean dosage for a fully breastfed infants was 68 mcg/kg daily or 0.2% of a pediatric dosage.[4] Infant Levels. Relevant published information was not found as of the revision date. Effects in Breastfed Infants At least 23 cases are reported in the literature in which infants (ages not stated) were breastfed during maternal ibuprofen use with no adverse effects reported.[1][3][5] Effects on Lactation and Breastmilk Relevant published information was not found as of the revision date. Alternate Drugs to Consider Acetaminophen , Flurbiprofen , Indomethacin , Naproxen , Piroxicam References 1. Weibert RT, Townsend RJ, Kaiser DG et al. Lack of ibuprofen secretion into human milk. Clin Pharm. 1982;1:457-8. PMID: 7184678 2. Townsend RJ, Benedetti TJ, Erickson SH et al. Excretion of ibuprofen into breast milk. Am J Obstet Gynecol. 1984;149:184-6. PMID: 6720796 3. Walter K, Dilger C. Ibuprofen in human milk. Br J Clin Pharmacol. 1997;44:211-2. PMID: 9278216 4. Rigourd V, de Villepin B, Amirouche A et al. Ibuprofen concentrations in human mature milk-First data about pharmacokinetics study in breast milk with AOR-10127 "Antalait" study. Ther Drug Monit. 2014;36:590-6. PMID: 24695355 5. Ito S, Blajchman A, Stephenson M. Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication. Am J Obstet Gynecol. 1993;168:1393-9. PMID: 8498418 Ibuprofen Identification Substance Name Ibuprofen CAS Registry Number 15687-27-1 Drug Class Analgesic Agents Nonsteroidal Antiinflammatory Agents Administrative Information LactMed Record Number 142 Last Revision Date 20160204 Disclaimer Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site. Print this page Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy. More about ibuprofen Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Compare Alternatives Support Group Pricing & Coupons 114 Reviews Add your own review/rating Drug class: nonsteroidal anti-inflammatory agents Consumer resources Ibuprofen Ibuprofen injection Ibuprofen Tablets Ibuprofen Capsules Ibuprofen Chewable Tablets ... +6 more Other brands: Advil , Motrin , IBU , Motrin IB , ... +23 more Professional resources Ibuprofen (AHFS Monograph) ... +8 more Related treatment guides Toothache Back Pain Headache Gout, Acute ... +21 more> ] Drug Status Rx OTC Availability Rx and/or OTC Pregnancy Category Risk depends on usage N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Ibuprofen Rating 114 User Reviews 7.5 /10 114 User Reviews 7.5 Rate it! Drug Class Nonsteroidal anti-inflammatory agents company
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