confidence decitabine (Intravenous route) dee-SYE-ta-been Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Dacogen Available Dosage Forms: Powder for Solution Therapeutic Class: Antineoplastic Agent Slideshow Leukemia Symptoms And Lessons: Is A Solution In Sight? Uses For decitabine Decitabine is used to treat myelodysplastic syndromes (diseases of the blood and bone marrow; MDS) and certain types of anemia. decitabine is an antineoplastic (cancer medicine) . decitabine is available only with your doctor's prescription . Before Using decitabine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For decitabine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to decitabine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of decitabine in the pediatric population. Safety and efficacy have not been established . Geriatric Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of decitabine in the elderly . Pregnancy Pregnancy Category Explanation All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of decitabine. Make sure you tell your doctor if you have any other medical problems, especially: Kidney disease or Liver disease Use with caution. Studies have not been done in patients with these conditions . Proper Use of decitabine Medicines used to treat cancer are very strong and can have many side effects. Before receiving decitabine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment . You will receive decitabine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you decitabine . decitabine is given through a needle placed into one of your veins . Precautions While Using decitabine It is very important that your doctor check your progress at regular visits to make sure that decitabine is working properly. Blood tests may be needed to check for unwanted effects . Using decitabine while you are pregnant can harm your unborn baby. The medicine may also cause birth defects if the father is using it when his sexual partner becomes pregnant. If a pregnancy occurs while you are using decitabine, tell your doctor right away. Men should not father a child while receiving decitabine, and for 2 months after the treatment . Cancer medicines can cause nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects . Decitabine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding: If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in urine or stools; or pinpoint red spots on your skin. Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done. Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime. Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters. Avoid contact sports or other situations where bruising or injury could occur . decitabine Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common Black, tarry stools bladder pain bleeding after defecation bleeding gums blood in urine or stools bloody or cloudy urine blue lips and fingernails blurred vision body aches or pain chest pain chills coma congestion convulsions cough coughing that sometimes produces a pink frothy sputum decreased urination difficult, burning, or painful urination difficult, fast, noisy breathing, sometimes with wheezing dizziness, faintness, or lightheadedness when getting up from a lying or sitting position drowsiness dry mouth dryness of throat facial swelling fainting fast or irregular heartbeat feeling unusually cold fever flushed, dry skin frequent urge to urinate fruit-like breath odor headache hives or welts hoarseness increased hunger increased sweating increased thirst increased urination itching, pain, redness, swelling, tenderness, or warmth on skin lightheadedness loss of appetite lower back or side pain mood or mental changes muscle pain or cramps muscle spasms or twitching nausea or vomiting nervousness numbness or tingling in hands, feet, or lips pale skin pinpoint red spots on skin redness or pain at the catheter site runny nose seizures shivering shortness of breath skin rash small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope small red or purple spots on skin, lips or in mouth sneezing sore mouth or tongue sore throat sores, ulcers, or white spots on lips or in mouth stomach pain and bloating sunken eyes swelling of face, hands, ankles, feet, or lower legs swollen, painful, or tender lymph glands in neck, armpit, or groin tightness in chest trembling trouble in swallowing troubled breathing with exertion uncomfortable swelling around anus unexplained weight loss unusual bleeding or bruising unusual tiredness or weakness voice changes weakness or heaviness of legs wheezing white patches in mouth and/or on tongue wrinkled skin yellow eyes or skin Less common Collection of blood under skin deep, dark purple bruise diarrhea pain or tenderness around eyes and cheekbones pain, warmth, or burning in fingers, toes, and legs problems with vision or hearing skin scrape or burn stuffy nose swelling at injection site Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Acid or sour stomach anxiety back pain belching bumps on skin burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings chest discomfort constipation difficulty swallowing fall hair loss, thinning of hair heartburn indigestion loose stools muscle stiffness pain in arms or legs pain in joints sleeplessness stomach discomfort or upset swelling or inflammation of the mouth trouble sleeping unable to sleep unusual drowsiness, dullness, or feeling of sluggishness Less common Difficulty in moving general feeling of discomfort or illness muscle aching pain in the tongue postnasal drip pressure in the stomach swollen joints Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about decitabine Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: antimetabolites Consumer resources Decitabine Other brands: Dacogen Professional resources Decitabine (AHFS Monograph) Decitabine (FDA) Decitabine (Wolters Kluwer) Related treatment guides Acute Myeloid Leukemia Myelodysplastic Syndrome} Drug Status Rx Availability Prescription only D Pregnancy Category Positive evidence of risk N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Dr. Reddy's Laboratories, Inc. Sun Pharmaceutical Industries Inc. Drug Class Antimetabolites Related Drugs Myelodysplastic Syndrome Vidaza , decitabine , azacitidine , Dacogen , More... Decitabine Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Related Questions & Answers Decitabine - Husband is to start this drug Monday. He has lymphoma and MDS. The last chemo we had? Myelodysplastic Syndrome - Has anyone undergone Dacogen, (Decitabine) treatment for MDS and if so? My husband has just been diagnosed with therapy-related MDS. He is getting decitabine every 4 weeks? Read more questions} } annoying
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