pattern calcifediol (Oral route) kal-sif-e-DYE-ol Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Rayaldee Available Dosage Forms: Capsule, Liquid Filled Capsule, Extended Release Therapeutic Class: Nutritive Agent Pharmacologic Class: Vitamin D (class) Slideshow Binge Eating Disorder: Beyond Overeating Uses For calcifediol Calcifediol is a vitamin D3 analog that is used to treat secondary hyperparathyroidism in adult patients with stage 3 or 4 chronic kidney disease and serum total 25-hydroxyvitamin D levels less than 30 ng/mL. Hyperparathyroidism is a condition that is caused when the parathyroid glands located in the neck make too much parathyroid hormone (PTH). This hormone helps to control the concentrations of calcium and phosphorus in your blood. calcifediol is available only with your doctor's prescription. Before Using calcifediol In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For calcifediol, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to calcifediol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of calcifediol in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of calcifediol in the elderly. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking calcifediol, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using calcifediol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Boceprevir Brivaracetam Carbamazepine Clarithromycin Clobazam Clonazepam Clorazepate Cobicistat Conivaptan Diazepam Eslicarbazepine Acetate Ethosuximide Ethotoin Ezogabine Felbamate Fosphenytoin Gabapentin Idelalisib Indinavir Itraconazole Ketoconazole Lacosamide Lamotrigine Levetiracetam Lopinavir Lorazepam Methsuximide Midazolam Nefazodone Nelfinavir Oxcarbazepine Perampanel Phenobarbital Phenytoin Posaconazole Pregabalin Primidone Ritonavir Rufinamide Saquinavir Stiripentol Telaprevir Telithromycin Tiagabine Topiramate Valproic Acid Vigabatrin Voriconazole Zonisamide Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of calcifediol. Make sure you tell your doctor if you have any other medical problems, especially: Bone problems Use with caution. May make these conditions worse. Hypercalcemia (high calcium in the blood), or history of Use with caution. May increase risk for cardiac arrhythmia and seizures. Proper Use of calcifediol Take calcifediol only as directed by your doctor . Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Swallow the extended-release capsule whole. Do not open, crush, break, or chew it. Dosing The dose of calcifediol will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of calcifediol. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (extended-release capsules): For secondary hyperparathyroidism: Adults 30 micrograms (mcg) (1 capsule) once a day, at bedtime. Your doctor may increase your dose as needed. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of calcifediol, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using calcifediol It is very important that your doctor check your progress at regular visits to make sure that calcifediol is working properly. Blood and other laboratory tests may be needed to check for unwanted effects. Hypercalcemia may occur while you are using calcifediol. Tell your doctor right away if you are feeling tired, trouble thinking clearly, loss of appetite, nausea, vomiting, constipation, increase thirst, increased urination, or weight loss. calcifediol may cause adynamic bone disease (low bone turnover) with high risk of fractures. Tell your doctor right away if you have pain or swelling in the arms or legs without any injury. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. calcifediol Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Abdominal or stomach pain chest pain confusion cough cough producing mucus decreased urine output difficulty with breathing difficulty with moving dilated neck veins extreme fatigue fever or chills irregular breathing irregular heartbeat muscle pain or stiffness nausea or vomiting nervousness numbness or tingling in the hands, feet, or lips pain, swelling, or redness in the joints pale skin sneezing sore throat swelling of the face, fingers, feet, or lower legs tightness in the chest troubled breathing with exertion unusual bleeding or bruising unusual tiredness or weakness weakness or heaviness of the legs weight gain Incidence not known Confusion constipation depression dry mouth headache incoherent speech increased urination loss of appetite metallic taste muscle weakness thirst weight loss Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Decreased appetite decreased urination dizziness dry mouth fainting high urine levels of calcium increase in heart rate irritability lightheadedness muscle weakness rapid breathing sunken eyes wrinkled skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Bruise muscle aches stuffy or runny nose Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about calcifediol Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 1 Review Add your own review/rating Drug class: vitamins Consumer resources Calcifediol Other brands: Rayaldee Professional resources Calcifediol (AHFS Monograph) Related treatment guides Renal Osteodystrophy Hyperparathyroidism Secondary to Renal Impairment Hypocalcemia} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Vitamins Related Drugs Hyperparathyroidism Secondary to Renal Impairment Rayaldee , Parsabiv , etelcalcetide , More... Hypocalcemia calcium carbonate , ergocalciferol , Caltrate , calcitriol , Vitamin D2 , Drisdol , Rocaltrol , More... Renal Osteodystrophy ergocalciferol , calcitriol , Vitamin D2 , Drisdol , Rocaltrol , Calcidol , More... Calcifediol Rating 1 User Review 10 /10 1 User Review 10 Rate it! Help and Support Looking for answers? Ask a question or go join the calcifediol support group to connect with others who have similar interests.} } sensible
contemporary calcifediol (Oral route) you should be
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