tail lamps Depo-Provera Contraceptive (Intramuscular) Generic Name: medroxyprogesterone (Intramuscular route) me-drox-ee-proe-JES-ter-one AS-e-tate Intramuscular route(Suspension) Women who use Depo-Provera CI (R) injection may lose significant bone mineral density. Bone loss is greater with increasing duration of use and may not be completely reversible. Depo-Provera CI (R) should not be used longer than 2 years unless other birth control methods are considered inadequate . Overview Side Effects Dosage Interactions Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Depo-Provera Depo-Provera Contraceptive Available Dosage Forms: Injectable Suspension Therapeutic Class: Antineoplastic Agent Pharmacologic Class: Medroxyprogesterone Slideshow Birth Control: Your Contraceptive Questions Answered Uses For Depo-Provera Contraceptive Medroxyprogesterone injection is used to prevent pregnancy. It is a birth control method that works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization is prevented. No contraceptive method is 100 percent effective. Birth control methods such as having surgery to become sterile or not having sex are more effective than birth control pills. Discuss your options for birth control with your doctor. This medicine does not prevent AIDS or other sexually transmitted diseases. It will not help as emergency contraception, such as after unprotected sexual contact. Medroxyprogesterone injection is also used with other medicines to help relieve symptoms of inoperable, recurrent, and metastatic (cancer that has already spread) endometrial or kidney cancer. This medicine is to be administered only by or under the immediate supervision of your doctor. Before Using Depo-Provera Contraceptive In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies on the relationship of age to the effects of Depo-Provera CI (contraceptive injection) have not been performed in the pediatric population. However, pediatric-specific problems that would limit the usefulness of this medicine in teenagers are not expected. This medicine may be used for birth control in teenage females, but should not be used before the start of menstruation. Appropriate studies have not been performed on the relationship of age to the effects of Depo-Provera in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies on the relationship of age to the effects of Depo-Provera CI (contraceptive injection) have not been performed in the geriatric population. This medicine should not be used in elderly women. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Depo-Provera in the elderly. Pregnancy Pregnancy Category Explanation All Trimesters X Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit. Breast Feeding Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Tranexamic Acid Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aprepitant Carbamazepine Dabrafenib Darunavir Isotretinoin Theophylline Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Amprenavir Atazanavir Bacampicillin Betamethasone Bexarotene Colesevelam Cyclosporine Delavirdine Efavirenz Fosamprenavir Fosaprepitant Lamotrigine Licorice Mycophenolate Mofetil Mycophenolic Acid Nelfinavir Prednisolone Rifapentine Ritonavir Rosuvastatin Rufinamide Selegiline Telaprevir Troleandomycin Warfarin Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Caffeine Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Abnormal or unusual vaginal bleeding Depo-Provera CI (contraceptive injection) should not be used in patients with this condition. Asthma or Breast cancer, family history of or Depression, history of or Diabetes or Eye disease or Fluid retention (edema or body swelling) or Heart disease or Hypertension (high blood pressure) or Kidney disease or Migraine headaches (severe headache) or Osteoporosis, current or risk factors for Use with caution. May make these conditions worse. Blood clots, or history of or Breast cancer, known or suspected or Liver disease, significant or Problems with circulation or blood clots, now or in the past or Stroke, now or in the past Should not be used in patients with these conditions. Proper Use of medroxyprogesterone This section provides information on the proper use of a number of products that contain medroxyprogesterone. It may not be specific to Depo-Provera Contraceptive. Please read with care. A nurse or other trained health professional will give you this medicine in a hospital or clinic. This medicine is given as a shot into one of your muscles (usually in the buttocks or upper arm). If you are using Depo-Provera : This medicine is initially given on a weekly basis, but the frequency may be less often over time. If you are using Depo-Provera CI (contraceptive injection): To make using hormonal contraceptives as safe and reliable as possible, you should understand how and when to use them and what effects may be expected. This medicine comes with patient information insert. Read them carefully and make sure you understand them before receiving this medicine. If you have any questions, ask your doctor. Your doctor must make sure you are not pregnant before you start treatment with this medicine. For most women, this means you must receive your first shot during the first 5 days of a normal menstrual period. You will need to receive this medicine every 3 months (12 to 14 weeks). Be sure to keep all appointments with your doctor to receive your injections. If you plan to start this medicine after having a baby, you should receive your first shot within 5 days after your baby is born. If you plan to breastfeed your new baby, talk to your doctor about when to get your first shot. Some doctors may suggest waiting 6 weeks before getting your first shot, but others may suggest getting the shot sooner after the baby is born. If you wait 6 weeks, talk to your doctor about using an alternative form of birth control. If you are switching from another method of birth control, carefully follow your doctor s instructions about when to have your first injection of this medicine. You need to have enough calcium and vitamin D in your diet. Your doctor might suggest that you take supplements. Missed Dose Call your doctor or pharmacist for instructions. You must have your shot of Depo-Provera CI (contraceptive injection) every 12 to 14 weeks to prevent pregnancy. If you do not get another shot after 14 weeks, talk with your doctor. You may need to use another form of birth control and wait until your next menstrual period before starting the shots again. Precautions While Using Depo-Provera Contraceptive It is very important that your doctor check your progress at regular visits when you are using Depo-Provera CI (contraceptive injection) to make sure this medicine is working properly and does not cause unwanted effects. These visits will usually be every 3 months, but some doctors require them more often. Your doctor will check your blood pressure once a year. Although you are using Depo-Provera CI (contraceptive injection) to prevent pregnancy, you should know that using this medicine while you are pregnant could harm the unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away. This medicine may cause your bones to lose calcium, which can lead to osteoporosis (thin or weak bones). This calcium loss could continue the whole time you are receiving this medicine. Your bones should start to rebuild calcium after you stop using this medicine. This is more of a concern if you are a teenager, smoke or drink alcohol regularly, have other bone problems, anorexia nervosa (an eating disorder), a family history of osteoporosis, or use other medicines that also affect your bones (such as steroids or medicine to treat seizures). You will need to talk with your doctor if you want to use this medicine for more than 2 years. You might need to be tested to make sure your bones are not losing too much calcium. Check with your doctor right away if you have pain in the chest, groin, or legs, especially the calves, difficulty with breathing, a sudden, severe headache, slurred speech, a sudden, unexplained shortness of breath, a sudden loss of coordination, or vision changes while using this medicine. Check with your doctor immediately if you have blurred vision, difficulty with reading, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor). There is a very slight chance that this medicine could increase risk of breast cancer in some women. Talk to your doctor about this risk. Make sure your doctor knows if anyone in your family has had breast cancer. Call your doctor right away if you have severe lower abdominal or stomach pain 3 to 5 weeks after receiving Depo-Provera CI (contraceptive injection). You may have a pregnancy outside of the uterus (womb), which is called an ectopic pregnancy. An ectopic pregnancy can be a serious and life-threatening condition. It can also cause problems that may make it harder for you to become pregnant in the future. Most women have changes in their menstrual periods while using Depo-Provera CI (contraceptive injection). You might have irregular bleeding, spotting, or heavier or lighter periods. Many women stop having periods. Call your doctor if you have very heavy or nonstop bleeding. This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving this medicine. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These could be symptoms of a serious liver problem. This medicine may cause fluid retention (edema) and weight gain in some patients. Tell your doctor right away if you have bloating or swelling of face, arms, hands, lower legs, or feet, tingling of hands or feet, or unusual weight gain or loss. Using these medicine may cause adrenal problems. Tell your doctor right away if you have darkening of the skin, diarrhea, nausea, or weight gain around your neck, upper back, breast, face, or waist. If you plan to have children after you stop using Depo-Provera CI (contraceptive injection), it may take up to year or longer before you can become pregnant. However, do not depend on this medicine to prevent pregnancy for more than 13 weeks. Depo-Provera CI (contraceptive injection) will not protect you from getting HIV/AIDS or other sexually transmitted infections. If this is a concern for you, talk with your doctor. Before you have any medical tests, tell the medical doctor in charge that you are using this medicine. The results of some tests may be affected by this medicine. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements. Depo-Provera Contraceptive Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common Absent, missed, or irregular menstrual periods menstrual changes stopping of menstrual bleeding Less common Breast pain cramps heavy bleeding increased clear or white vaginal discharge itching of the vagina or genital area pain during sexual intercourse swelling thick, white vaginal discharge with no odor or with a mild odor Incidence not known Abdominal or stomach pain anxiety black, tarry stools blood in the stools burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings changes in skin color chest pain chills clay-colored stools clear or bloody discharge from the nipple cough dark urine decrease in height difficult or labored breathing difficulty with breathing difficulty with swallowing dimpling of the breast skin dizziness or lightheadedness dull ache or feeling of pressure or heaviness in the legs fainting fast, pounding, or irregular heartbeat or pulse fever general feeling of discomfort or illness headache hives, itching, or rash increased thirst inverted nipple itching skin near damaged veins loss of appetite lump in the breast or under the arm nausea no sensation in the legs noisy breathing pain in the back, ribs, arms, or legs pain, redness, tenderness, or swelling of the arm, foot, or leg pale skin persistent crusting or scaling of the nipple puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue redness or swelling of the breast sore on the skin of the breast that does not heal sudden shortness of breath or troubled breathing swelling swollen feet and ankles tightness in the chest troubled breathing with exertion unable to move the legs unpleasant breath odor unusual bruising or bleeding unusual tiredness or weakness vomiting of blood yellow eyes or skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abdominal or stomach discomfort decreased interest in sexual intercourse inability to have or keep an erection increased weight loss in sexual ability, desire, drive, or performance nervousness Less common Backache blemishes on the skin bloating depression difficulty with moving feeling of warmth hair loss or thinning of the hair lack or loss of strength leg cramps muscle pain or stiffness pain in the joints pimples redness of the face, neck, arms, and occasionally, upper chest sudden sweating trouble sleeping Incidence not known Brown, blotchy spots on the exposed skin changes in appetite diarrhea drowsiness dry skin hoarseness increased hair growth, especially on the face increased in sexual ability, desire, drive, or performance increased interest in sexual intercourse increased sweating and body odor indigestion loss of appetite pain, tenderness, dimpling or indentation of the skin, or lump at the injection site passing of gas patchy brown or dark brown discoloration of the skin stomach pain, fullness, or discomfort swelling of the armpits unexpected or excess milk flow from breasts Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. 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Next Side Effects Print this page Add to My Med List More about Depo-Provera Contraceptive (medroxyprogesterone) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 7 Reviews Add your own review/rating Drug class: contraceptives Consumer resources Depo-Provera Contraceptive injection Professional resources Medroxyprogesterone Acetate (AHFS Monograph) Medroxyprogesterone Injection (FDA) Other Formulations Provera Depo-Provera Depo-SubQ Provera 104 injection Related treatment guides Abnormal Uterine Bleeding Amenorrhea Birth Control Endometrial Cancer Endometrial Hyperplasia, Prophylaxis Endometriosis} Drug Status Rx Availability Prescription only X Pregnancy Category Not for use in pregnancy N/A CSA Schedule Not a controlled drug Drug Class Contraceptives Hormones / antineoplastics Progestins Related Drugs Abnormal Uterine Bleeding Premarin , megestrol , Megace , medroxyprogesterone , Provera , Depo-Provera , More... Amenorrhea progesterone , medroxyprogesterone , Provera , Depo-Provera , Prometrium , norethindrone , More... Birth Control medroxyprogesterone , Provera , Depo-Provera , norethindrone , Mirena , Nexplanon , More... Endometrial Hyperplasia, Prophylaxis progesterone , medroxyprogesterone , Provera , Depo-Provera , Prometrium , Crinone , More... 2 more conditions... Depo-Provera Contraceptive Rating 7 User Reviews 4.8 /10 7 User Reviews 4.8 Rate it! Related Questions & Answers Depo-Provera - How soon after the shot of Depo-Provera is it effective in preventing pregnancy? Depo-Provera Contraceptive - I gained 40kg in the month following commencement of depo-provera. This Depo-Provera - One shot only and periods are still missing? Depo-Provera Contraceptive - I am due my depo this week can I still have intercourse? Read more questions} } prompted
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