well-merited Dicyclomine Side Effects Overview Side Effects Dosage Professional Tips More Interactions Pregnancy Warnings Breastfeeding Warnings User Reviews Drug Images Support Group Q & A Compare Alternatives Pricing & Coupons For the Consumer Applies to dicyclomine: oral capsules and tablets, oral solution, parenteral injection Side effects include: Most adverse effects are manifestations of pharmacologic effects at muscarinic-cholinergic receptors and usually are reversible when therapy is discontinued. Severity and frequency of adverse effects are dose related and individual intolerance varies greatly; although adverse effects occasionally may be obviated by a reduction in dosage, this also will likely eliminate potential therapeutic effects. If dosage of 80 mg daily cannnot be achieved because of intolerance, discontinue dicyclomine. Dry mouth, dizziness, blurred vision, nausea, light-headedness (especially with the injectable form), drowsiness, weakness, nervousness. For Healthcare Professionals Applies to dicyclomine: compounding powder, intramuscular solution, oral capsule, oral syrup, oral tablet General -The most serious adverse reactions include cardiovascular and central nervous system symptoms. -The most common adverse reactions are dizziness, dry mouth, vision blurred, nausea, somnolence, asthenia and nervousness, fever, tachycardia, agitation, and dry skin/mucous membranes. [ Ref ] Gastrointestinal Very common (10% or more): Dry mouth (33%), nausea (14%) Rare (less than 0.1%): Constipation, anorexia Frequency not reported: Thirst, delayed gastric emptying time, reduced gastric acid secretion, gastroesophageal reflux Postmarketing reports: Abdominal distension, abdominal pain, dyspepsia, constipation, dry mouth, nausea, vomiting [ Ref ] Nervous system Very common (10% or more): Dizziness (40%) Common (1% to 10%): Somnolence, nervousness Rare (less than 0.1%): Sedation, headache Postmarketing reports: Dizziness, headache, somnolence, syncope [ Ref ] Ocular Very common (10% or more): Blurred vision (27%) Frequency not reported: Follicular conjunctivitis, all muscarinic antagonists can precipitate glaucoma Postmarketing reports: Cycloplegia, mydriasis, blurred vision [ Ref ] Other Common (1% to 10%): Asthenia Frequency not reported: Fatigue Postmarketing reports: Malaise, fatigue [ Ref ] Dermatologic Rare (less than 0.1%): Rash Postmarketing reports: Allergic dermatitis, erythema, rash [ Ref ] Renal Rare (less than 0.1%): Dysuria [ Ref ] Genitourinary Frequency not reported: Urinary retention, impotence in male patients Postmarketing reports: Suppressed lactation [ Ref ] Cardiovascular Postmarketing reports: Palpitations, tachyarrhythmias, thrombosis, thrombophlebitis [ Ref ] Hypersensitivity Postmarketing reports: Face edema, angioedema, anaphylactic shock [ Ref ] Local Postmarketing reports: Local pain, edema, skin color change, reflex sympathetic dystrophy syndrome (caused by inadvertent IV injection) [ Ref ] Psychiatric Postmarketing reports: Delirium or symptoms of delirium such as amnesia (or transient global amnesia), nervousness, agitation, confusional state, delusion, disorientation, hallucination (including visual hallucination), and mania, mood (altered and pseudodementia). [ Ref ] Respiratory Postmarketing reports: Dyspnea, nasal congestion [ Ref ] References 1. Kagan G, Huddlestone L, Wolstencroft P "Comparison of dicyclomine with antacid and without antacid in dyspepsia." J Int Med Res 12 (1984): 174-8 2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 3. "Product Information. Bentyl (dicyclomine)." Aventis Pharmaceuticals, Kansas City, MO. Some side effects of dicyclomine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA . Next Dosage Print this page More about dicyclomine Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Compare Alternatives Support Group Pricing & Coupons En EspaƱol 162 Reviews Add your own review/rating Drug class: anticholinergics/antispasmodics Consumer resources Dicyclomine Dicyclomine Capsules Dicyclomine Syrup and Oral Solution Dicyclomine Tablets Dicyclomine Injection Other brands: Bentyl Professional resources Dicyclomine Hydrochloride (AHFS Monograph) ... +5 more Related treatment guides Irritable Bowel Syndrome Noninfectious Colitis Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Lannett Company, Inc. Mylan Pharmaceuticals Inc. Teva Pharmaceuticals USA, Inc. Drug Class Anticholinergics / antispasmodics Related Drugs Irritable Bowel Syndrome dicyclomine , Amitiza , Bentyl , Metamucil , psyllium , hyoscyamine , Levsin , Librax , lubiprostone , Donnatal , chlordiazepoxide / clidinium , Levbid , Konsyl , Anaspaz , alosetron , HyoMax , Lotronex , Levsin SL , Antispasmodic , Hyosyne , Reguloid , More... Dicyclomine Rating 162 User Reviews 7.8 /10 162 User Reviews 7.8 Rate it! Dicyclomine Images Dicyclomine systemic 20 mg (WATSON 795 ) View all images this type of
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