an excellent Dicyclomine use while Breastfeeding Drugs containing Dicyclomine: Bentyl, Dicyclocot, Bentyl Syrup, Bemote, Byclomine, Di-Spaz, Dibent, Dilomine Overview Side Effects Dosage Professional Tips More Interactions Pregnancy Warnings Breastfeeding Warnings User Reviews Drug Images Support Group Q & A Compare Alternatives Pricing & Coupons Dicyclomine Levels and Effects while Breastfeeding Summary of Use during Lactation Dicyclomine has not been well studied during breastfeeding. However, one possible case of apnea has been reported in a breastfed infant that is similar to reactions that have occurred in infants given the drug directly.[1] Dicyclomine should not be used during lactation. Drug Levels Maternal Levels. Relevant published information was not found as of the revision date. However, the manufacturer reported a mother who was given a single 20 mg dose of dicyclomine orally. Two hours after the dose, the concentration in breastmilk was 131 mcg/L.[1] Infant Levels. Relevant published information was not found as of the revision date. Effects in Breastfed Infants Relevant published information was not found as of the revision date. The manufacturer reported a breastfed infant who developed apnea during maternal therapy with dicyclomine.[1] Dicyclomine is a possible cause of the reaction. Effects on Lactation and Breastmilk Relevant published information in nursing mothers was not found as of the revision date. Anticholinergics can inhibit lactation in animals, apparently by inhibiting growth hormone and oxytocin secretion.[2][3][4][5][6] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[7] The prolactin level in a mother with established lactation may not affect her ability to breastfeed. References 1. Briggs GG, Freeman RK, Yaffe SJ. Drugs in pregnancy and lactation, 7th ed. Baltimore. Williams & Wilkins. 2005. 2. Aaron DK, Ely DG, Deweese WP et al. Reducing milk production in ewes at weaning using restricted feeding and methscopolamine bromide. J Anim Sci. 1997;75:1434-42. PMID: 9250502 3. Powell MR, Keisler DH. A potential strategy for decreasing milk production in the ewe at weaning using a growth hormone release blocker. J Anim Sci. 1995;73:1901-5. PMID: 7592071 4. Daniel JA, Thomas MG, Powell MR, Keisler DH. Methscopolamine bromide blocks hypothalmic-stimulated release of growth hormone in ewes. J Anim Sci. 1997;75:1359-62. PMID: 9159285 5. Bizzarro A, Iannucci F, Tolino A et al. Inhibiting effect of atropine on prolactin blood levels after stimulation with TRH. Clin Exp Obstet Gynecol. 1980;7:108-11. PMID: 6788407 6. Svennersten K, Nelson L, Juvnas-Moberg K. Atropinization decreases oxytocin secretion in dairy cows. Acta Physiol Scand. 1992;145:193-4. PMID: 1636447 7. Masala A, Alagna S, Devilla L et al. Muscarinic receptor blockade by pirenzepine: effect on prolactin secretion in man. J Endocrinol Invest. 1982;5:53-5. PMID: 6808052 Dicyclomine Identification Substance Name Dicyclomine CAS Registry Number 77-19-0 Drug Class Muscarinic Antagonists Parasympatholytics Administrative Information LactMed Record Number 570 Last Revision Date 20170411 Disclaimer Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site. Print this page Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy. More about dicyclomine Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Compare Alternatives Support Group Pricing & Coupons En Español 162 Reviews Add your own review/rating Drug class: anticholinergics/antispasmodics Consumer resources Dicyclomine Dicyclomine Capsules Dicyclomine Syrup and Oral Solution Dicyclomine Tablets Dicyclomine Injection Other brands: Bentyl Professional resources Dicyclomine Hydrochloride (AHFS Monograph) ... +5 more Related treatment guides Irritable Bowel Syndrome Noninfectious Colitis Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Dicyclomine Rating 162 User Reviews 7.8 /10 162 User Reviews 7.8 Rate it! Drug Class Anticholinergics / antispasmodics reliable
polishing off Dicyclomine use while Breastfeeding is definite
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