remedies RibaPak (Oral) Generic Name: ribavirin (Oral route) rye-ba-VYE-rin Overview Side Effects Dosage Interactions Pregnancy More User Reviews Support Group Q & A Pricing & Coupons Oral route(Tablet;Capsule;Solution) Ribavirin monotherapy is ineffective for treatment of chronic hepatitis C virus infection. The primary toxicity is hemolytic anemia, which may result in worsening of cardiac disease and fatal and nonfatal myocardial infarctions. Avoid use in patients with significant or unstable cardiac disease. Significant teratogenic and embryocidal effects have been demonstrated in all animal species exposed to ribavirin. Ribavirin is contraindicated in women who are pregnant and in male partners of women who are pregnant. Use 2 reliable forms of contraception and avoid pregnancy during therapy and for 6 months after completion of treatment in both female patients and in female partners of male patients who are taking ribavirin . Commonly used brand name(s) In the U.S. Copegus Rebetol RibaPak Ribasphere Ribasphere Ribapak RibaTab Available Dosage Forms: Tablet Solution Capsule Therapeutic Class: Antiviral Pharmacologic Class: Viral RNA Polymerase Inhibitor Chemical Class: Guanosine Nucleoside Analog Slideshow Think Before You Ink: Health Risks Associated With Tattoos Uses For RibaPak Ribavirin is used in combination with injectable interferon alfa-2b, peginterferon alfa-2a, or peginterferon alfa-2b to treat chronic hepatitis C infection. The combination of ribavirin and peginterferon alfa-2b is used to treat adults and children 3 years of age and older who show symptoms of liver damage. Ribavirin is an antiviral agent that treats hepatitis C virus. This medicine is available only with your doctor's prescription. Before Using RibaPak In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of ribavirin tablets in children younger than 5 years of age, ribavirin capsules and oral liquid in children younger than 3 years of age. The safety and efficacy of ribavirin tablets, capsules, and oral liquid have not been established in these age groups. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ribavirin in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require an adjustment in the dose for patients receiving ribavirin. Pregnancy Pregnancy Category Explanation All Trimesters X Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Didanosine Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Abacavir Azathioprine Mercaptopurine Stavudine Zalcitabine Zidovudine Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Interferon Alfa-2b Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Autoimmune hepatitis (liver inflammation) or Heart disease (unstable), or history of or Liver disease (including cirrhosis), severe or Sickle cell anemia (red blood cell disorder) or Thalassemia major (genetic blood disorder) Should not be used in patients with these conditions. Blood or bone marrow problems (e.g., anemia, pancytopenia) or Breathing problems and lung disease (e.g., pneumonia, pulmonary infiltrates, pulmonary hypertension) or Colitis (inflammation of the colon) or Depression or Diabetes or Drug abuse, history of or Eye or vision problems (e.g., loss of vision, retinopathy) or Heart attack, history of or Heart or blood vessel disease, history of or Hypertension (high blood pressure) or Pancreatitis (inflammation of the pancreas) or Sarcoidosis (lung disease) or Thyroid disease or Weakened immune system Use with caution. May make these conditions worse. Blood problems (e.g., spherocytosis) or Stomach problems (e.g., bleeding), history of Use with caution. May increase risk for severe anemia. Infection (e.g., adenovirus, RSV) or Influenza or parainfluenza Copegus should not be used in patients with these conditions. Your doctor may give you inhaled ribavirin. Kidney disease Higher blood levels of ribavirin can occur, which increases the risk of serious side effects. Liver disease, decompensated or Organ transplant (e.g., liver, kidney) Use of ribavirin and peginterferon alfa-2a combination have not been established in patients with these conditions. Proper Use of ribavirin This section provides information on the proper use of a number of products that contain ribavirin. It may not be specific to RibaPak. Please read with care. To help clear up your infection completely, ribavirin must be given for the full time of treatment , even if you or your child begins to feel better after a few days. Also, it is important to keep the amount of medicine in your body at a steady level. To help keep the amount constant, ribavirin must be given on a regular schedule. You should take this medicine with food. Swallow the capsule whole. Do not crush, break, or open it. Measure the oral liquid with a marked measuring cup or spoon. Wash the cup or spoon after each use. This medicine should come with a Medication Guide. Read and follow the information carefully. Ask your doctor if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For hepatitis C virus infection, in combination with interferon alfa-2b: For oral dosage form (capsules): Adults Dose is based on body weight and must be determined by your doctor. The dose is usually 1000 to 1200 milligrams (mg) per day, given as two or three capsules in the morning and three capsules at night. Children 3 years of age and older Dose is based on body weight and must be determined by your doctor. The dose is usually 15 milligrams (mg) per kilogram (kg) of body weight per day, given in 2 divided doses and taken in the morning and evening. Children younger than 3 years of age Use and dose must be determined by your doctor. For oral dosage form (solution): Adults Dose is based on body weight and must be determined by your doctor. The oral solution form of this medicine is not usually prescribed for adults and teenagers. Children 3 years of age and older Dose is based on body weight and must be determined by your doctor. The dose is usually 15 milligrams (mg) per kilogram (kg) of body weight per day, given in 2 divided doses and taken in the morning and evening. Children younger than 3 years of age Use and dose must be determined by your doctor. For hepatitis C virus infection, in combination with peginterferon alfa-2b: For oral dosage form (capsules): Adults Dose is based on body weight and must be determined by your doctor. The dose is usually 800 to 1400 milligrams (mg) per day, given as two to three capsules in the morning and two to four capsules at night. Children 3 years of age and older Dose is based on body weight and must be determined by your doctor. The dose is usually 15 milligrams (mg) per kilogram (kg) of body weight per day, given in 2 divided doses and taken in the morning and evening. Children younger than 3 years of age Use and dose must be determined by your doctor. For oral dosage form (solution): Adults Dose is based on body weight and must be determined by your doctor. The oral solution form of this medicine is not usually prescribed for adults and teenagers. Children 3 years of age and older Dose is based on body weight and must be determined by your doctor. The dose is usually 15 milligrams (mg) per kilogram (kg) of body weight per day, given in two divided doses and taken in the morning and evening. Children younger than 3 years of age Use and dose must be determined by your doctor. For hepatitis C virus infection, in combination with peginterferon alfa-2a: For oral dosage form (tablets): Adults Dose is based on body weight and must be determined by your doctor. The dose is usually 800 to 1200 milligrams (mg) per day, given in 2 divided doses and taken in the morning and evening. Children 5 years of age and older Dose is based on body weight and must be determined by your doctor. The dose is usually 400 to 1200 mg per day, given in 2 divided doses and taken in the morning and evening. Children younger than 5 years of age Use and dose must be determined by your doctor. For hepatitis C with HIV virus coinfection, in combination with peginterferon alfa-2a: For oral dosage form (tablets): Adults 800 milligrams (mg) per day. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Store the capsules and tablets in a closed container at room temperature, away from heat, moisture, and direct light. Store the oral liquid in the refrigerator or at room temperature, away from heat and direct light. Do not freeze. Precautions While Using RibaPak It is very important that your doctor check the progress of you or your child at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects. Using this medicine while you are pregnant can harm your unborn baby. The medicine may also cause birth defects if the father is using it when his sexual partner becomes pregnant. If a pregnancy occurs while you are using this medicine, tell your doctor right away. It is important to tell your doctor if you or your female sexual partner become pregnant. Your doctor may want you to join a pregnancy registry for patients taking this medicine. A negative pregnancy test is needed in women who are of childbearing age before starting treatment with this medicine. Two forms of birth control must be used together during treatment and for 6 months after treatment ends. You will need to have pregnancy tests done regularly to make sure you are not pregnant while being treated with this medicine and after your treatment ends. Do not use Copegus in combination with didanosine (Videx , Videx EC). Using these medicines together may cause serious medical problems. Ribavirin may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you, your child, or your caregiver notice any of these side effects, tell your doctor or your child's doctor right away. Check with your doctor right away if you or your child have back, leg, or stomach pains; bleeding gums; chills; dark urine; difficulty breathing; fever; general body swelling; headache; loss of appetite; nausea or vomiting; nosebleeds; pale skin; sore throat; unusual tiredness or weakness; or yellowing of the eyes or skin. These could be symptoms of a blood disorder called anemia. This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Stop taking this medicine and call your doctor right away if you or your child have itching, hives, hoarseness, trouble with breathing, trouble with swallowing, or any swelling of the hands, face, or mouth while you are using this medicine. Serious skin reactions can occur with this medicine. Check with your doctor right away if you or your child have blistering, peeling, or loosening of the skin; fever or chills; hives or welts; red skin lesions; a severe skin rash or acne; or sores or ulcers on the skin while you are using this medicine. Pancreatitis may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you or your child have sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness. You or your teenager should not drink alcoholic beverages (including beer, wine, or liquor) while you are taking this medicine. This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you or your teenager drive, operate machinery, or do anything else that could be dangerous if you are not alert . Check with your doctor if blurred vision, decreased vision, or any other change in vision occurs while you or your child are using this medicine . Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor). Peginterferon injection combined with ribavirin can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets in the blood, which are necessary for proper blood clotting. If this occurs, there are certain precautions you or your child can take, especially when your blood count is low, to reduce the risk of infection or bleeding: If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots on your skin. Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done. Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime. Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters. Avoid contact sports or other situations where bruising or injury could occur. This medicine may cause teeth and gum problems. This medicine may cause dryness of the mouth, and a dry mouth may damage your teeth and gums if you take the medicine for a long time. To help prevent this condition, carefully brush your teeth at least two times a day and have regular visits with your dentist. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. Some patients who have used this medicine have had vomiting. If you vomit during your treatment, rinse your mouth out with water. This may also help prevent damage to your teeth and gums. Ribavirin used together with injectable peginterferon alfa-2a or peginterferon alfa-2b may affect your child's growth. Your doctor may need to check your child's height and weight during and after treatment with these medicines. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. RibaPak Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Anxiety black, tarry stools body aches or pain chest pain congestion cough or hoarseness crying depersonalization diarrhea difficult or labored breathing discouragement dry mouth dryness of the throat dysphoria euphoria feeling sad or empty feeling unusually cold fever or chills general feeling of discomfort or illness headache hyperventilation irregular heartbeats irritability joint pain lack of appetite loss of interest or pleasure lower back or side pain mental depression muscle aches and pains nausea nervousness painful or difficult urination pale skin paranoia poor concentration quick to react or overreact emotionally rapidly changing moods restlessness right upper abdominal or stomach pain runny nose shaking shivering shortness of breath sleeplessness sore throat sores, ulcers, or white spots on the lips or in the mouth sweating tender, swollen glands in the neck tightness in the chest trouble with concentrating trouble with sleeping trouble with swallowing troubled breathing with exertion unable to sleep unusual bleeding or bruising unusual tiredness or weakness voice changes vomiting wheezing Less common Bleeding gums blood in the urine or stools constipation depressed mood dry skin and hair feeling cold hair loss husky voice muscle cramps and stiffness pinpoint red spots on the skin right upper abdominal or stomach fullness slowed heartbeat weight gain Incidence not known Blistering, flaking, or peeling of the skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Acid or sour stomach being forgetful belching blurred vision bone pain change in taste or bad, unusual, or unpleasant (after) taste cracked, scaly skin crusting, irritation, itching, or reddening of the skin difficulty with moving dizziness or lightheadedness feeling of constant movement of self or surroundings hair loss or thinning of the hair heartburn indigestion lack or loss of strength menstrual changes pain or tenderness around the eyes and cheekbones rash sensation of spinning sneezing stomach discomfort, upset, or pain stuffy nose swelling swollen joints weight loss Less common Back pain burning, dry, or itching eyes discharge, excessive tearing feeling of warmth redness of the face, neck, arms, and occasionally, upper chest redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid skin rash, encrusted, scaly, and oozing Incidence not known Change in hearing loss of hearing Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. 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Next Side Effects Print this page Add to My Med List More about RibaPak (ribavirin) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 0 Reviews Add your own review/rating Drug class: inhaled anti-infectives Consumer resources RibaPak Other brands: Ribasphere , Rebetol , Moderiba , Virazole , ... +2 more Professional resources Ribavirin (AHFS Monograph) Ribavirin Inhalation Solution (FDA) Related treatment guides Hepatitis C} Drug Status Rx Availability Prescription only X Pregnancy Category Not for use in pregnancy N/A CSA Schedule Not a controlled drug Manufacturer Three Rivers Pharmaceuticals, LLC Drug Class Inhaled anti-infectives Purine nucleosides Related Drugs Hepatitis C Harvoni , Epclusa , ribavirin , Zepatier , Mavyret , Sovaldi , sofosbuvir , ledipasvir / sofosbuvir , Vosevi , Viekira Pak , daclatasvir , Daklinza , Pegasys , Intron A , Ribasphere , Olysio , sofosbuvir / velpatasvir , Rebetol , simeprevir , Moderiba , PegIntron , elbasvir / grazoprevir , glecaprevir / pibrentasvir , More... RibaPak Rating No Reviews - Be the first! 1.0 /10 No Reviews - Be the first! 1.0 Rate it! Related Questions & Answers Will be starting pegasys and ribapak 600mg in 5 days. have heard horrible things about it. if there? I have a friend who lives outside the U.S. that needs ribapak to treat hepitits C..it is nit? Read more questions} } latest
straight away RibaPak (Oral) many differing types
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