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severely Rythmol SR (Oral) Generic Name: propafenone (Oral route) proe-PA-fen-one hye-droe-KLOR-ide Oral route(Tablet;Capsule, Extended Release) It is prudent to consider any Class 1C antiarrhythmic to have a significant proarrhythmic risk in patients with structural heart disease. Given the lack of any evidence that these drugs improve survival, antiarrhythmic agents should generally be avoided in patients with non-life-threatening ventricular arrhythmias, even if the patients are experiencing unpleasant, but not life-threatening, symptoms or signs . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Rythmol Rythmol SR Available Dosage Forms: Capsule, Extended Release Tablet Therapeutic Class: Antiarrhythmic, Group IC Chemical Class: Propafenone Slideshow Atrial Fibrillation - Stroke Prevention Guidelines & Treatment Options Uses For Rythmol SR Propafenone is used to prevent irregular heartbeats such as atrial fibrillation (AF) from occurring again in patients who do not have structural heart disease. Propafenone belongs to the group of medicines known as antiarrhythmics. It works directly on the heart tissue and will slow the nerve impulses in the heart. This helps keep the heart rhythm normal. There is a chance that propafenone may cause new or make worse existing heart rhythm problems when it is used. Since it has been shown to cause severe problems in some patients, propafenone is only used to treat serious heart rhythm problems. Discuss this possible effect with your doctor. This medicine is available only with your doctor's prescription. Before Using Rythmol SR In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of propafenone in the pediatric population. Safety and efficacy have not been established. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of propafenone in the elderly. Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Amifampridine Amisulpride Bepridil Cisapride Dronedarone Fluconazole Ketoconazole Levomethadyl Mesoridazine Nelfinavir Pimozide Piperaquine Posaconazole Ritonavir Saquinavir Sparfloxacin Terfenadine Thioridazine Tipranavir Vernakalant Ziprasidone Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acecainide Ajmaline Alfuzosin Amiodarone Amitriptyline Amoxapine Anagrelide Apomorphine Aprindine Aripiprazole Aripiprazole Lauroxil Arsenic Trioxide Artemether Asenapine Astemizole Azimilide Azithromycin Boceprevir Bretylium Bupropion Buserelin Ceritinib Chloral Hydrate Chloroquine Chlorpromazine Ciprofloxacin Citalopram Clarithromycin Clomipramine Clozapine Cobicistat Crizotinib Dabrafenib Dasabuvir Dasatinib Degarelix Delamanid Delavirdine Desipramine Deslorelin Deutetrabenazine Dibenzepin Digoxin Disopyramide Dofetilide Dolasetron Domperidone Donepezil Droperidol Duloxetine Efavirenz Eltrombopag Enflurane Erythromycin Escitalopram Etravirine Fingolimod Flecainide Fluoxetine Foscarnet Gatifloxacin Gemifloxacin Gonadorelin Goserelin Granisetron Halofantrine Haloperidol Halothane Histrelin Hydroquinidine Hydroxychloroquine Hydroxyzine Ibutilide Idelalisib Iloperidone Imipramine Isoflurane Isradipine Ivabradine Lapatinib Leuprolide Levofloxacin Lidocaine Lidoflazine Lopinavir Lorcainide Lumefantrine Mefloquine Methadone Metronidazole Mifepristone Mirabegron Mirtazapine Moxifloxacin Nafarelin Nilotinib Norfloxacin Nortriptyline Octreotide Ombitasvir Ondansetron Paliperidone Panobinostat Paritaprevir Paroxetine Pasireotide Pazopanib Pentamidine Pimavanserin Pirmenol Pitolisant Prajmaline Prilocaine Probucol Procainamide Prochlorperazine Promethazine Propafenone Protriptyline Quetiapine Quinidine Quinine Ranolazine Ribociclib Risperidone Salmeterol Sematilide Sertindole Sertraline Sevoflurane Simeprevir Sodium Phosphate Sodium Phosphate, Dibasic Sodium Phosphate, Monobasic Solifenacin Sorafenib Sotalol Spiramycin Sulfamethoxazole Sulpiride Sultopride Sunitinib Tacrolimus Tedisamil Telaprevir Telithromycin Tetrabenazine Tizanidine Toremifene Trazodone Trifluoperazine Trimethoprim Trimipramine Triptorelin Vandetanib Vardenafil Vasopressin Vemurafenib Vinflunine Voriconazole Zolmitriptan Zotepine Zuclopenthixol Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Cyclosporine Rifampin Rifapentine Theophylline Tolterodine Warfarin Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Grapefruit Juice Tobacco Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Asthma or Bronchitis or Emphysema Propafenone can increase trouble in breathing. AV block (type of abnormal heart rhythm), with no pacemaker or Bradycardia (slow heartbeat) or Breathing problems or lung disease (eg, bronchospasm, severe obstructive pulmonary disease) or Brugada syndrome (a genetic heart rhythm disorder) or Cardiogenic shock (shock caused by heart attack) or Heart failure or Hypotension (low blood pressure) or Mineral imbalance or Sick sinus node syndrome (type of abnormal heart rhythm), with no pacemaker Should not be used in patients with these conditions. Blood or bone marrow problems (eg, agranulocytosis, granulocytopenia) or Coronary artery disease or Heart rhythm problems (eg, QT prolongation) or Myasthenia gravis (severe muscle weakness) or Torsade de pointes or Ventricular fibrillation or tachycardia Use with caution. May make these conditions worse. Kidney disease or Liver disease Use with caution. The effects may be increased because of slower removal of the medicine from the body. If you have a permanent pacemaker Use with caution. Propafenone may interfere with the pacemaker and require more careful follow-up by the doctor. Proper Use of propafenone This section provides information on the proper use of a number of products that contain propafenone. It may not be specific to Rythmol SR. Please read with care. Take this medicine exactly as directed by your doctor . Do not take more or less of this medicine, and do not take it more often than your doctor ordered. This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions. For patients taking the extended-release capsules : Swallow the capsules whole. Do not crush, break, or chew them. This medicine may be taken with or without food. This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take each dose at evenly spaced times day and night. For example, if you are to take 3 doses a day, doses should be spaced about 8 hours apart. If you need help in planning the best times to take your medicine, check with your doctor. Your doctor may want you to carry a medical identification card or bracelet stating that you are using this medicine. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. The number of extended-release capsules or tablets that you take depends on the strength of the medicine. For atrial fibrillation (AF): For oral dosage form (extended-release capsules): Adults At first, 225 milligrams (mg) every 12 hours. Your doctor may adjust your dose as needed. However, the dose is usually not more than 425 mg every 12 hours. Children Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults 150 milligrams (mg) every 8 hours. Your doctor may increase your dose if needed. Children Use and dose must be determined by your doctor. Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Rythmol SR It is important that your doctor check your progress at regular visits to make sure the medicine is working properly. This will allow for changes to be made in the amount of medicine you are taking, if necessary. This medicine can cause changes in your heart rhythm, such as conditions called PR, QRS, or QT prolongation. It may cause fainting or serious side effects in some patients. Contact your doctor right away if your symptoms do not improve or if they get worse. Check with your doctor right away if you develop any of the following: chest pain, shortness of breath, swelling of your hands, ankles, or feet, or weight gain. These may be symptoms of heart failure. This medicine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests. Propafenone may cause some people to become dizzy or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy . If you have been using this medicine regularly for several weeks, do not suddenly stop using it. Check with your doctor for the best way to gradually reduce the amount you are taking before stopping completely. This medicine may decrease the amount of sperm men make. Talk to your doctor if you have concerns about this. Grapefruits and grapefruit juice may increase the effects of propafenone by increasing the amount of this medicine in your body. You should not eat grapefruit or drink grapefruit juice while you taking this medicine. Tell your doctor if you are smoking tobacco. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Rythmol SR Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Chest pain fast, irregular, or slow heartbeat lightheadedness, dizziness, or fainting shortness of breath swelling of the feet or lower legs weight gain Rare Chills fever joint pain trembling or shaking weakness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Change in taste or bitter or metallic taste Less common Blurred vision constipation diarrhea dryness of the mouth headache nausea or vomiting skin rash unusual tiredness or weakness Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about Rythmol SR (propafenone) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 16 Reviews Add your own review/rating Generic Availability Drug class: group I antiarrhythmics Consumer resources Rythmol SR Professional resources Rythmol Extended Release (FDA) Rythmol SR (FDA) Propafenone Hydrochloride (AHFS Monograph) Other Formulations Rythmol Related treatment guides Atrial Fibrillation Atrial Flutter Ventricular Tachycardia Wolff-Parkinson-White Syndrome} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturer GlaxoSmithKline Drug Class Group I antiarrhythmics Related Drugs Atrial Fibrillation diltiazem , Xarelto , propranolol , digoxin , sotalol , flecainide , More... Wolff-Parkinson-White Syndrome flecainide , propafenone , Rythmol , adenosine , Tambocor , Adenocard , More... Atrial Flutter diltiazem , sotalol , flecainide , Multaq , propafenone , Rythmol , More... Ventricular Tachycardia atenolol , propranolol , amiodarone , lidocaine , flecainide , Tenormin , More... Rythmol SR Rating 16 User Reviews 8.9 /10 16 User Reviews 8.9 Rate it! Rythmol SR Images Rythmol SR 225 mg (a 225 ) View all images Related Questions & Answers Rythmol SR - After wearing an Event Monitor for 21 days a cardiologist has scripted Coumadin and? I have been on Rthymol SR 225 mg twice a day since September 6, 2011? Does Rythmol SR suppress heart rate while exercising? Read more questions} } considered necessary


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