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captivating Tolcapone Pregnancy and Breastfeeding Warnings Tolcapone is also known as: Tasmar Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Tolcapone Pregnancy Warnings Animal studies have revealed evidence of an increased rate of abortion, decreased litter size, and impaired growth and learning performance. Evidence of maternal toxicity including death has been reported. Also in animal studies, concomitant use of levodopa/carbidopa with tolcapone produced an increased incidence of fetal malformations (primarily external and skeletal digit defects) when compared to levodopa/carbidopa alone. Decreased fetal body weights were also reported. There are no controlled data in human pregnancy. FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. FDA pregnancy category: C Potential benefit should outweigh potential risk. Women of childbearing potential should be encouraged to use adequate contraception. See references Tolcapone Breastfeeding Warnings Caution is recommended. Excreted into human milk: Unknown Excreted into animal milk: Yes The effects in the nursing infant are unknown. See references References for pregnancy information "Product Information. Tasmar (tolcapone)." Roche Laboratories, Nutley, NJ. References for breastfeeding information "Product Information. Tasmar (tolcapone)." Roche Laboratories, Nutley, NJ. Print this page See Also... tolcapone Consumer Information Pregnancy Support Group FDA Pregnancy Categories Medicine use during Pregnancy Medicine use while Breastfeeding Safe Medications during Breastfeeding Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist. Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Tolcapone Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Drug Class Dopaminergic antiparkinsonism agents Help and Support Looking for answers? Ask a question or go join the tolcapone support group to connect with others who have similar interests. hit upon


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