awakened atovaquone and proguanil Generic Name: atovaquone and proguanil (a TOE va kwone and pro GWAHN il) Brand Name: Malarone, Malarone Pediatric Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons What is atovaquone and proguanil? Atovaquone and proguanil are medications to treat malaria, a disease caused by parasites. These medicines work by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. The combination of atovaquone and proguanil is used to treat or prevent malaria. Atovaquone and proguanil may also be used for purposes not listed in this medication guide. Slideshow It s Buggin Me! How to Safely Use an Insect Repellent What is the most important information I should know about atovaquone and proguanil? You should not use this medication if you are allergic to atovaquone or proguanil. You should not use this medication to prevent malaria if you have severe kidney disease. Before using this medication, tell your doctor if you have liver or kidney disease, severe complications from infection with malaria, or uncontrolled vomiting or diarrhea. Take atovaquone and proguanil at the same time each day with food or a milky drink. If you vomit within 1 hour after taking this medication, take another dose. If your vomiting continues, call your doctor. If you are taking this medicine to prevent malaria, start taking it 1 or 2 days before entering an area where malaria is common. Take the medication every day during your stay and for at least 7 days after you leave. If you stop taking the medicine early for any reason, contact a healthcare professional about another form of malaria prevention. If you are taking this medicine to treat malaria, take the medication every day for 3 days in a row. Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. In addition to taking atovaquone and proguanil, use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could cause malaria. Contact your doctor as soon as possible if you have been exposed to malaria, or if you have a fever or other symptoms of illness during or after a stay in an area where malaria is common. No medication is 100% effective in treating or preventing malaria. For best results, keep using the medication as directed. Talk with your doctor if you have fever, vomiting, or diarrhea during your treatment. What should I discuss with my healthcare provider before taking atovaquone and proguanil? You should not use this medication if you are allergic to atovaquone or proguanil. You should not use this medication to prevent malaria if you have severe kidney disease. To make sure you can safely take atovaquone and proguanil, tell your doctor if you have any of these other conditions: kidney disease; liver disease; severe complications from malaria; or uncontrolled vomiting or diarrhea. FDA pregnancy category C. It is not known whether atovaquone and proguanil will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Malaria is more likely to cause death in a pregnant woman. If you are pregnant, talk with your doctor about the risks of traveling to areas where malaria is common. Atovaquone and proguanil can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Atovaquone and proguanil should not be used to treat malaria in a child who weighs less than 11 pounds, and should not be used to prevent malaria in a child who weighs less than 24 pounds. How should I take atovaquone and proguanil? Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Use atovaquone and proguanil regularly to best prevent malaria. If you stop using the medication early for any reason, talk to your doctor about other forms of malaria prevention. Take atovaquone and proguanil at the same time each day with food or a milky drink. If you vomit within 1 hour after taking this medication, take another dose. If your vomiting continues, call your doctor. If you are taking this medicine to prevent malaria: Start taking the medicine 1 or 2 days before entering an area where malaria is common. Continue taking the medicine every day during your stay and for at least 7 days after you leave the area. If you stop taking the medicine early for any reason, contact a healthcare professional about another form of malaria prevention. If you are taking this medicine to treat malaria: Take the medicine every day for 3 days in a row. Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. In addition to taking atovaquone and proguanil, use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could cause malaria. To be sure this medication is not causing harmful effects, your liver function will need to be checked with frequent blood tests. Visit your doctor regularly. Contact your doctor as soon as possible if you have been exposed to malaria, or if you have fever or other symptoms of illness during or after a stay in an area where malaria is common. No medication is 100% effective in treating or preventing malaria. For best results, keep using the medication as directed. Talk with your doctor if you have fever, vomiting, or diarrhea during your treatment. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include stomach discomfort, vomiting, mouth sores, hair loss, easy bruising or bleeding, and peeling of the skin on your hands or feet. What should I avoid while taking atovaquone and proguanil? Follow your doctor's instructions about any restrictions on food, beverages, or activity. Atovaquone and proguanil side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as: severe or uncontrolled vomiting or diarrhea; fever, mouth sores; problems with speech, balance, or walking; severe skin rash; nausea, stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); o easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin. Less serious side effects may include: mild stomach pain or upset stomach; mild diarrhea; headache; mild itching; weakness; or dizziness. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) Atovaquone and proguanil dosing information Usual Adult Dose for Malaria: 1 g atovaquone/400 mg proguanil (four adult strength tablets as a single dose) orally once a day for 3 consecutive days Usual Adult Dose for Malaria Prophylaxis: Prophylactic therapy should start 1 or 2 days before entering a malaria-endemic area and continued daily during the stay and for 7 days after return. 250 mg atovaquone/100 mg proguanil (one adult strength tablet) orally once a day Usual Pediatric Dose for Malaria: Less than 5 kg ABW (actual body weight): Safety and efficacy has not been established. 5 to 8 kg ABW: 125 mg atovaquone/50 mg proguanil (2 pediatric tablets) once daily for 3 consecutive days. 9 to 10 kg ABW: 187.5 mg atovaquone/75 mg proguanil (3 pediatric tablets) once daily for 3 consecutive days. 11 to 20 kg ABW: 250 mg atovaquone/100 mg proguanil (one adult strength or four pediatric tablets as a single dose) orally once a day for 3 consecutive days 21 to 30 kg ABW: 500 mg atovaquone/200 mg proguanil (two adult strength tablets as a single dose) orally once a day for 3 consecutive days 31 to 40 kg ABW: 750 mg atovaquone/300 mg proguanil (three adult strength tablets as a single dose) orally once a day for 3 consecutive days Greater than 40 kg ABW: 1 g atovaquone/400 mg proguanil (four adult strength tablets as a single dose) orally once a day for 3 consecutive days Usual Pediatric Dose for Malaria Prophylaxis: Prophylactic treatment should start 1 or 2 days before entering a malaria-endemic area and continued daily during the stay and for 7 days after return. 11 to 20 kg ABW (actual body weight): 62.5 mg atovaquone/25 mg proguanil (one pediatric tablet) orally once a day 21 to 30 kg ABW: 125 mg atovaquone/50 mg proguanil (two pediatric tablets as a single dose) orally once a day 31 to 40 kg ABW: 187.5 mg atovaquone/75 mg proguanil (three pediatric tablets as a single dose) orally once a day Greater than 40 kg ABW: 250 mg atovaquone/100 mg proguanil (one adult strength tablet) orally once a day What other drugs will affect atovaquone and proguanil? Tell your doctor about all other medicines you use, especially: a blood thinner such as warfarin (Coumadin); rifabutin (Mycobutin); rifampin (Rifadin, Rifater, Rifamate, Rimactane); tetracycline (Brodspec, Panmycin, Sumycin, Tetracap); or metoclopramide (Reglan). This list is not complete and other drugs may interact with atovaquone and proguanil. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Next Side Effects Print this page Add to My Med List More about atovaquone/proguanil Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 24 Reviews Add your own review/rating Drug class: antimalarial combinations Consumer resources Atovaquone and Proguanil Atovaquone and proguanil (Advanced Reading) Other brands: Malarone , Malarone Pediatric Professional resources Atovaquone and Proguanil Hydrochloride (AHFS Monograph) Atovaquone and Proguanil (FDA) Atovaquone and Proguanil (Wolters Kluwer) Related treatment guides Malaria Prevention Malaria Where can I get more information? Your pharmacist can provide more information about atovaquone and proguanil. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 5.02. Last reviewed: December 15, 2010 Date modified: December 03, 2017} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Manufacturers Mylan Pharmaceuticals Inc. Prasco Laboratories Glenmark Pharmaceuticals Inc., USA Drug Class Antimalarial combinations Related Drugs Malaria Prevention doxycycline , hydroxychloroquine , Plaquenil , Vibramycin , Malarone , Monodox , mefloquine , atovaquone / proguanil , Doryx , pyrimethamine , More... Malaria doxycycline , hydroxychloroquine , clindamycin , Plaquenil , Cleocin , Vibramycin , quinine , Malarone , atovaquone , Monodox , quinidine , More... Atovaquone / proguanil Rating 24 User Reviews 5.9 /10 24 User Reviews 5.9 Rate it! Atovaquone / proguanil Images Atovaquone / proguanil systemic 250 mg / 100 mg (G 404) View all images Related Questions & Answers Atovaquone/Proguanil - Does this medication need to be taken each time you travel or is it good for? Read more questions} } gives you
latest atovaquone and proguanil vary size-wise
EmoticonEmoticon