many people Tipiracil / trifluridine Side Effects Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A For the Consumer Applies to tipiracil / trifluridine: oral tablet Along with its needed effects, tipiracil / trifluridine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking tipiracil / trifluridine: More common Black, tarry stools bleeding gums blood in the urine or stools cough or hoarseness fever or chills lower back or side pain painful or difficult urination pale skin pinpoint red spots on the skin sore throat troubled breathing with exertion ulcers, sores, or white spots in the mouth unusual bleeding or bruising unusual tiredness or weakness Less common Bladder pain bloody or cloudy urine frequent urge to urinate headache muscle aches stuffy or runny nose Some side effects of tipiracil / trifluridine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abdominal or stomach pain change in taste decreased appetite diarrhea hair loss or thinning of the hair lack or loss of strength loss of taste nausea swelling or inflammation of the mouth vomiting For Healthcare Professionals Applies to tipiracil / trifluridine: oral tablet Hematologic Very common (10% or more): Anemia (77%), neutropenia (67%), thrombocytopenia (42%) Common (1% to 10%): Febrile neutropenia [ Ref ] Other Very common (10% or more): Asthenia/fatigue (52%), infections (27%), pyrexia (19%) [ Ref ] Gastrointestinal Very common (10% or more): Nausea (48%), diarrhea (32%), vomiting (28%), abdominal pain (21%) Common (1% to 10%): Stomatitis (8%) [ Ref ] General 3.6% of patients discontinued treatment for an adverse event; 13.7% required a dose reduction, most commonly for neutropenia, anemia, febrile neutropenia, fatigue, and diarrhea. [ Ref ] Respiratory Common (1% to 10%): Nasopharyngitis, pulmonary emboli Uncommon (0.1% to 1%): Interstitial lung disease [ Ref ] Metabolic Very common (10% or more): Decreased appetite (39%) [ Ref ] Cardiovascular Common (1% to 10%): QTc interval prolongation [ Ref ] Nervous system Common (1% to 10%): Dysgeusia [ Ref ] Genitourinary Common (1% to 10%): Urinary tract infections [ Ref ] Dermatologic Common (1% to 10%): Alopecia [ Ref ] References 1. "Product Information. Lonsurf (tipiracil-trifluridine)." Taiho Oncology, Inc., Princeton, NJ. Some side effects of tipiracil / trifluridine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA . Next Dosage Print this page More about tipiracil/trifluridine Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: antineoplastic combinations Consumer resources Tipiracil and trifluridine Trifluridine and Tipiracil Trifluridine and tipiracil (Advanced Reading) Other brands: Lonsurf Professional resources Trifluridine and Tipiracil Hydrochloride (AHFS Monograph) Trifluridine and Tipiracil (Wolters Kluwer) Related treatment guides Colorectal Cancer Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. 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Drug Status Rx Availability Prescription only N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Antineoplastic combinations Related Drugs Colorectal Cancer Avastin , fluorouracil , Xeloda , capecitabine , Opdivo , leucovorin , Keytruda , nivolumab , oxaliplatin , bevacizumab , Erbitux , Betaseron , pembrolizumab , irinotecan , Stivarga , cetuximab , Lonsurf , Cyramza , Camptosar , Vectibix , regorafenib , Eloxatin , ramucirumab , levoleucovorin calcium , Fusilev , More... Tipiracil / trifluridine Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! recommendations
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