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clearly sargramostim (Intravenous route) sar-GRA-moe-stim Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Commonly used brand name(s) In the U.S. Leukine Available Dosage Forms: Powder for Solution Solution Therapeutic Class: Hematopoietic Pharmacologic Class: Colony Stimulating Factor Slideshow Donate Life: What You Need To Know About Organ Donorship Uses For sargramostim Sargramostim is a synthetic (man-made) version of a substance that is naturally produced in your body called a colony stimulating factor. It helps the bone marrow to make new white blood cells . When certain cancer medicines are used to fight cancer cells, they also affect the white blood cells that fight infections. Sargramostim is used to prevent or reduce the risk of infection while you are being treated with cancer medicines. sargramostim is also used to help the bone marrow recover after a bone marrow transplantation, and for a process called peripheral blood progenitor cell collection in cancer patients . sargramostim is available only with your doctor's prescription . Before Using sargramostim In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For sargramostim, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to sargramostim or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies performed to date have not demonstrated pediatrics-specific problems that would limit the usefulness of sargramostim in children. However, safety and efficacy have not been established in babies younger than 4months of age . Geriatric Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of sargramostim in the elderly . Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving sargramostim, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using sargramostim with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Vincristine Vincristine Sulfate Liposome Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of sargramostim. Make sure you tell your doctor if you have any other medical problems, especially: Bone marrow hyperplasia Should not be used. Will result to higher risk of serious side effect in patients with this condition . Congestive heart failure or Edema (fluid retention) or Heart disease or Heart rhythm problems, history of or Hypoxia (decreased oxygen in the tissues) or Kidney disease or Liver disease or Lung disease or breathing problems or Pericardial effusion (fluid around the heart) or Pleural effusion (fluid around the lungs) Use with caution. May make these conditions worse . Proper Use of sargramostim A nurse or other trained health professional may give you sargramostim. Your doctor will prescribe your exact dose and tell you how often it should be given. sargramostim is given through a needle placed in one of your veins . Precautions While Using sargramostim It is very important that your doctor check your progress at regular visits to make sure that sargramostim is working properly. Blood tests may be needed to check for unwanted effects . Tell your doctor about all the other medicines you are using, especially if you are being treated for cancer. sargramostim should not be given at the same time as chemotherapy or radiotherapy or within 24 hours before or after you receive your cancer treatment . sargramostim Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common Abdominal pain black, tarry stools bloating or swelling of face, arms, hands, lower legs, or feet blood in eye bloody nose bloody stools blurred vision body aches or pain bone pain chest pain cloudy urine congestion cough decrease in urine output or decrease in urine-concentrating ability difficult or labored breathing drowsiness dry mouth dryness or soreness of throat eye pain fast, pounding, or irregular heartbeat or pulse fatigue fever flushed, dry skin fruit-like breath odor hoarseness increased hunger increased thirst increased urination irregular heartbeat large amount of cholesterol in the blood loss of appetite mood or mental changes muscle spasms [tetany] or twitching seizures nausea or vomiting rapid weight gain redness in whites of eyes runny nose shortness of breath sweating tender, swollen glands in neck tightness in chest tingling of hands or feet trouble in swallowing troubled breathing trembling unusual tiredness or weakness unusual weight gain or loss voice changes vomiting of blood or material that looks like coffee grounds wheezing yellow eyes or skin Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose General feeling of discomfort or illness headache rash Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Chills diarrhea difficulty in moving fear or nervousness itching skin lack or loss of strength muscle pain or stiffness pain in joints sleeplessness trouble sleeping unable to sleep Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Copyright 2017 Truven Health Analytics, Inc. All Rights Reserved. Next Side Effects Print this page Add to My Med List More about sargramostim Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En EspaƱol 0 Reviews Add your own review/rating Drug class: colony stimulating factors Consumer resources Sargramostim Other brands: Leukine Professional resources Sargramostim (AHFS Monograph) Sargramostim (Wolters Kluwer) Related treatment guides Aplastic Anemia Bone Marrow Transplantation Bone Marrow Transplantation, Failure or Engraftment Delay Bone Marrow Transplantation, Myeloid Reconstruction Neutropenia Associated with Chemotherapy} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Colony stimulating factors Related Drugs Neutropenia Associated with Chemotherapy Neulasta , Neupogen , filgrastim , Zarxio , Granix , pegfilgrastim , More... Aplastic Anemia Promacta , eltrombopag , Leukine , Atgam , sargramostim , lymphocyte immune globulin, anti-thy (equine) , More... Bone Marrow Transplantation fluconazole , Diflucan , cisplatin , Neupogen , filgrastim , Zarxio , More... Bone Marrow Transplantation, Failure or Engraftment Delay Leukine , sargramostim , More... 1 more conditions... Sargramostim Rating No Reviews - Be the first! No Reviews - Be the first! Not Rated - Be the first! Help and Support Looking for answers? Ask a question or go join the sargramostim support group to connect with others who have similar interests.} } years to come


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