muscle tissue nadolol and bendroflumethiazide (Oral route) NAY-doe-lol, ben-droe-floo-me-THYE-a-zide Oral route(Tablet) Following abrupt cessation of therapy with certain beta-blocking agents, exacerbations of angina pectoris and, in some cases, myocardial infarction have occurred. The dosage should be gradually reduced over 1 to 2 weeks, and the patient should be carefully monitored when discontinuing chronic therapy, particularly in patients with ischemic heart disease. If angina markedly worsens or acute coronary insufficiency develops, nadolol should be reinstated promptly, at least temporarily, and other measures appropriate for the management of unstable angina should be taken. Patients should be warned against interruption or discontinuation of therapy without the physician's advice . Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Drug Images Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Corzide Available Dosage Forms: Tablet Therapeutic Class: Beta-Adrenergic Blocker, Nonselective/Thiazide Combination Pharmacologic Class: Beta-Adrenergic Blocker, Nonselective Chemical Class: Thiazide Slideshow Can Prescription Drugs Lead to Weight Gain? Uses For nadolol and bendroflumethiazide Nadolol and bendroflumethiazide combination is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled . Nadolol is a beta-blocker. It works by affecting the response to some nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart . Bendroflumethiazide is a diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps lower the blood pressure . nadolol and bendroflumethiazide is available only with your doctor's prescription . Before Using nadolol and bendroflumethiazide In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For nadolol and bendroflumethiazide, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to nadolol and bendroflumethiazide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of nadolol and bendroflumethiazide combination in the pediatric population. Safety and efficacy have not been established . Geriatric Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of nadolol and bendroflumethiazide combination in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require an adjustment of dosage in patients receiving nadolol and bendroflumethiazide combination . Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking nadolol and bendroflumethiazide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using nadolol and bendroflumethiazide with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Aceclofenac Acemetacin Acetyldigoxin Amtolmetin Guacil Arsenic Trioxide Aspirin Bepridil Bromfenac Bufexamac Celecoxib Choline Salicylate Clonidine Clonixin Crizotinib Deslanoside Dexibuprofen Dexketoprofen Diclofenac Diflunisal Digitalis Digitoxin Digoxin Diltiazem Dipyrone Dofetilide Dronedarone Droperidol Droxicam Epinephrine Etodolac Etofenamate Etoricoxib Felbinac Fenoldopam Fenoprofen Fepradinol Feprazone Fingolimod Flecainide Floctafenine Flufenamic Acid Flurbiprofen Ibuprofen Indacaterol Indomethacin Ketanserin Ketoprofen Ketorolac Lacosamide Levomethadyl Lidocaine Lithium Lornoxicam Loxoprofen Lumiracoxib Meclofenamate Mefenamic Acid Meloxicam Metildigoxin Morniflumate Nabumetone Naproxen Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Oxaprozin Oxymetazoline Oxyphenbutazone Parecoxib Phenylbutazone Piketoprofen Piroxicam Proglumetacin Propyphenazone Proquazone Rivastigmine Rofecoxib Salicylic Acid Salsalate Sodium Salicylate Sotalol Sulindac Tenoxicam Tiaprofenic Acid Tolfenamic Acid Tolmetin Valdecoxib Verapamil Using nadolol and bendroflumethiazide with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acarbose Aceclofenac Acemetacin Acetyldigoxin Albiglutide Alfuzosin Alogliptin Aminolevulinic Acid Amiodarone Amtolmetin Guacil Arbutamine Aspirin Bromfenac Bufexamac Bunazosin Canagliflozin Celecoxib Chlorpropamide Choline Salicylate Clonixin Dapagliflozin Deslanoside Dexibuprofen Dexketoprofen Diclofenac Diflunisal Digitoxin Digoxin Dipyrone Doxazosin Droxicam Dulaglutide Empagliflozin Etodolac Etofenamate Etoricoxib Exenatide Felbinac Fenoprofen Fepradinol Feprazone Floctafenine Flufenamic Acid Flurbiprofen Ginkgo Glimepiride Glipizide Glyburide Gossypol Ibuprofen Indomethacin Insulin Aspart, Recombinant Insulin Degludec Insulin Detemir Insulin Glargine, Recombinant Insulin Glulisine Insulin Human Inhaled Insulin Human Isophane (NPH) Insulin Human Regular Insulin Lispro, Recombinant Ketoprofen Ketorolac Licorice Linagliptin Liraglutide Lixisenatide Lornoxicam Loxoprofen Lumiracoxib Meclofenamate Mefenamic Acid Meloxicam Metformin Metildigoxin Mibefradil Miglitol Morniflumate Moxisylyte Nabumetone Naproxen Nateglinide Nepafenac Niflumic Acid Nimesulide Nimesulide Beta Cyclodextrin Oxaprozin Oxyphenbutazone Parecoxib Phenelzine Phenoxybenzamine Phentolamine Phenylbutazone Piketoprofen Pioglitazone Piroxicam Pramlintide Pranoprofen Prazosin Proglumetacin Propyphenazone Proquazone Repaglinide Rofecoxib Rosiglitazone Salicylic Acid Salsalate Saxagliptin Sitagliptin Sodium Salicylate St John's Wort Sulindac Tamsulosin Tenoxicam Terazosin Tiaprofenic Acid Tolazamide Tolbutamide Tolfenamic Acid Tolmetin Trimazosin Urapidil Valdecoxib Vildagliptin Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using nadolol and bendroflumethiazide with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use nadolol and bendroflumethiazide, or give you special instructions about the use of food, alcohol, or tobacco. Green Tea Other Medical Problems The presence of other medical problems may affect the use of nadolol and bendroflumethiazide. Make sure you tell your doctor if you have any other medical problems, especially: Angina (severe chest pain) May provoke chest pain if stopped too quickly . Anuria (not able to form urine) or Asthma or Bradycardia (slow heartbeat) or Heart block or Heart failure Should not use in patients with these conditions . Blood vessel disease (circulation problems) or Gout or Hyperuricemia (high uric acid in the blood) or Hypochloremia (low chloride in the blood) or Hypokalemia (low potassium in the blood) or Hypomagnesemia (low magnesium in the blood) or Hyponatremia (low sodium in the blood) or Parathyroid disease or Systemic lupus erythematosus Use with caution. nadolol and bendroflumethiazide may make these conditions worse . Diabetes or Hyperthyroidism (overactive thyroid) or Hypoglycemia (low blood sugar) May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat . Kidney disease, severe or Liver disease Use with caution. The effects may be increased because of slower removal of the medicine from the body . Lung disease (e.g., bronchitis, emphysema) May cause difficulty with breathing in patients with this condition . Sympathectomy Use with caution. The effects of nadolol and bendroflumethiazide may be increased . Proper Use of nadolol and bendroflumethiazide In addition to the use of nadolol and bendroflumethiazide, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet . Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well . Remember that nadolol and bendroflumethiazide will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease . Do not interrupt or stop taking nadolol and bendroflumethiazide without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. Some conditions may become worse when the medicine is stopped suddenly, which can be dangerous . Dosing The dose of nadolol and bendroflumethiazide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of nadolol and bendroflumethiazide. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets): For high blood pressure: Adults One tablet once a day. Your doctor may adjust your dose if needed. Children Use and dose must be determined by your doctor . Missed Dose If you miss a dose of nadolol and bendroflumethiazide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using nadolol and bendroflumethiazide It is very important that your doctor check your progress at regular visits to make sure nadolol and bendroflumethiazide is working properly and to check for unwanted effects . nadolol and bendroflumethiazide may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; weight gain; or wheezing . nadolol and bendroflumethiazide may cause changes in your blood sugar levels. Also, nadolol and bendroflumethiazide may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems or if you notice a change in the results of your blood or urine sugar tests . Make sure any doctor or dentist who treats you knows that you are using nadolol and bendroflumethiazide. You may need to stop using nadolol and bendroflumethiazide several days before having surgery or medical tests . nadolol and bendroflumethiazide Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Blurred vision burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings chest pain or discomfort confusion cough difficulty breathing dilated neck veins dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly extreme fatigue irregular breathing lightheadedness, dizziness, or fainting noisy breathing paleness or cold feeling in fingertips and toes shortness of breath slow or irregular heartbeat slurred speech sweating swelling of face, fingers, feet, or lower legs tightness in chest tingling or pain in fingers or toes when exposed to cold unusual tiredness or weakness weight gain wheezing Incidence not determined Back or leg pains black, tarry stools bleeding gums bloating blood in urine or stools chills clay-colored stools cloudy urine cold sweats constipation coughing up blood dark urine difficulty swallowing drowsiness dry mouth fast heartbeat fever flushed, dry skin fruit-like breath odor general body swelling general feeling of discomfort or illness general tiredness and weakness headache hives hoarseness increased hunger increased thirst increased urination indigestion joint pain, stiffness, or swelling light-colored stools loss of appetite lower back or side pain muscle tremors nausea and vomiting nosebleeds pain in muscles painful or difficult urination pains in stomach, side, or abdomen, possibly radiating to the back pale skin pinpoint red spots on skin puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue rapid, deep breathing rash redness, soreness, or itching skin restlessness skin rash sore throat sores, ulcers, or white spots on lips or in mouth sores, welting or blisters stomach cramps sugar in the urine swollen or painful glands tenderness of salivary glands thickening of bronchial secretions troubled breathing unpleasant breath odor unusual bleeding or bruising unusual weight loss upper right abdominal pain vomiting of blood yellow eyes or skin Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Change in consciousness decreased urination diarrhea fast, slow, or shallow breathing gas heartburn increase in heart rate increased sweating indigestion loss of consciousness low blood pressure muscle cramps numbness, tingling, pain, or weakness in hands or feet pale or blue lips, fingernails, or skin seizures sunken eyes trembling unusual drowsiness, dullness, or feeling of sluggishness unusual paleness weakness and heaviness of legs wrinkled skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Change in behavior continuing ringing or buzzing or other unexplained noise in ears decreased interest in sexual intercourse dry eyes or skin excess air or gas in stomach or intestines hair loss, thinning of hair hearing loss inability to have or keep an erection loss in sexual ability, desire, drive, or performance relaxed and calm sleepiness stomach soreness or discomfort stuffy nose weight loss Incidence not determined Cracks in the skin discoloration of skin feeling of constant movement of self or surroundings increased sensitivity of skin to sunlight large, flat, blue or purplish patches in the skin loss of heat from the body muscle spasm, weakness, or restlessness scaly skin sensation of spinning severe sunburn Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. 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Next Side Effects Print this page Add to My Med List More about bendroflumethiazide/nadolol Side Effects During Pregnancy Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Español 1 Review Add your own review/rating Drug class: beta blockers with thiazides Consumer resources Bendroflumethiazide and nadolol Nadolol and Bendroflumethiazide Other brands: Corzide , Corzide 40/5 , Corzide 80/5 Professional resources Nadolol and Bendroflumethiazide (FDA) Nadolol and Bendroflumethiazide (Wolters Kluwer) Related treatment guides High Blood Pressure} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA WADA Class Anti-Doping Classification Manufacturer Global Pharmaceuticals Drug Class Beta blockers with thiazides Related Drugs High Blood Pressure amlodipine , lisinopril , hydrochlorothiazide , furosemide , losartan , metoprolol , atenolol , Lasix , Norvasc , valsartan , enalapril , Diovan , Cozaar , Benicar , Toprol-XL , Bystolic , irbesartan , Lopressor , hydrochlorothiazide / lisinopril , hydrochlorothiazide / triamterene , Maxzide , Zestril , Dyazide , More... Bendroflumethiazide / nadolol Rating 1 User Review 10 /10 1 User Review 10 Rate it! Bendroflumethiazide / nadolol Images Bendroflumethiazide / nadolol systemic 5mg / 40mg (M 96 ) View all images Help and Support Looking for answers? Ask a question or go join the bendroflumethiazide / nadolol support group to connect with others who have similar interests.} } one of these
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