retain Macugen (Intraocular) Generic Name: pegaptanib (Intraocular route) peg-AP-ta-nib Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Pricing & Coupons Commonly used brand name(s) In the U.S. Macugen Available Dosage Forms: Solution Therapeutic Class: Ophthalmologic Agent Slideshow A Joint Effort: A Provider's Guide To Orthopedic Pain Options Uses For Macugen Pegaptanib is used to treat neovascular (wet) age-related macular degeneration (AMD). AMD is a disorder of the retina of the eye that causes blurring of vision or blindness . This medicine is available only with your doctor's prescription . Before Using Macugen In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of pegaptanib in the pediatric population. Safety and efficacy have not been established . Geriatric Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of pegaptanib in the elderly . Pregnancy Pregnancy Category Explanation All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Breast Feeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with Food/Tobacco/Alcohol Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Eye infection Pegaptanib should NOT be used in patients with an infection in or around the eye . Glaucoma This medicine may increase eye pressure after injection. Your doctor will monitor your eye pressure during the week after every injection . Proper Use of Macugen A doctor will give you this medicine. Pegaptanib is given through a shot into your eye. . Precautions While Using Macugen Your doctor will want to check your progress at regular visits , especially during the first few weeks that you receive this medicine . Serious eye problems may occur after treatment with this medicine. Check with your doctor immediately if your eye becomes red, sensitive to light, painful or develops a change in vision several days after your treatment . Macugen Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common Bladder pain blindness bloody eye bloody or cloudy urine blurred vision burning, dry, or itching eyes cough producing mucus decreased vision or other changes in vision difficult, burning, or painful urination difficulty breathing discharge, excessive tearing disturbed color perception double vision drainage from eyes eye pain frequent urge to urinate gradual loss of vision halos around lights itching of eyelid looking through water lower back or side pain nausea night blindness overbright appearance of lights painful irritation of the clear front part of the eye redness, pain, swelling of eye, eyelid, or inner lining of eyelid seeing flashes or sparks of light seeing floating spots before the eyes shortness of breath sore eyes swelling of the eye tightness in chest tunnel vision vomiting wheezing Less Common Bigger, dilated, or enlarged pupils (black part of the eye) change in vision not present before treatment chest pain confusion decrease in frequency of urination decrease in urine volume difficulty in passing urine (dribbling) dizziness or lightheadedness dry mouth eye irritation fatigue feeling of constant movement of self or surroundings flushed, dry skin fruit-like breath odor headache hearing loss inability to speak increased hunger increased sensitivity of eyes to light increased thirst increased urination loss of consciousness numbness or tingling in face, arms, or legs seeing floaters, veil or curtain appearing across part of vision seizures sensation of spinning severe or sudden headache slurred speech stomachache sweating temporary blindness trouble speaking, thinking, or walking troubled breathing unexplained weight loss weakness in arm and/or leg on one side of the body, sudden and severe Incidence not determined Difficulty swallowing fast heartbeat hives itching puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue skin rash unusual tiredness or weakness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Diarrhea Less common Acid or sour stomach belching blistering, burning, crusting, dryness, or flaking of skin bruise difficulty in moving heartburn indigestion itching, scaling, severe redness, soreness, swelling of skin muscle pain or stiffness pain, swelling, or redness in joints stomach discomfort, upset, or pain Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects (complete list) The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. 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Next Side Effects Print this page Add to My Med List More about Macugen (pegaptanib ophthalmic) Side Effects During Pregnancy Dosage Information Drug Interactions Support Group Pricing & Coupons En Español 1 Review Add your own review/rating Drug class: anti-angiogenic ophthalmic agents Consumer resources Macugen Professional resources Macugen (AHFS Monograph) Macugen (FDA) Related treatment guides Macular Degeneration} Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Manufacturers Gilead Sciences, Inc. Valeant Pharmaceuticals International, Inc. Drug Class Anti-angiogenic ophthalmic agents Related Drugs Macular Degeneration Eylea , Lucentis , aflibercept ophthalmic , ranibizumab ophthalmic , pegaptanib ophthalmic , Visudyne , More... Macugen Rating 1 User Review 9.0 /10 1 User Review 9.0 Rate it! Related Questions & Answers Can macugen cause severe head aches after long term use? 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