person that daclatasvir Generic Name: daclatasvir (dak LAT as vir) Brand Name: Daklinza Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A What is daclatasvir? Daclatasvir is an antiviral medicine that prevents hepatitis C virus (HCV) from multiplying in your body. Daclatasvir is used to treat genotype 3 chronic hepatitis C in adults without cirrhosis. This medicine is given together with another drug called sofosbuvir. Daclatasvir may also be used for purposes not listed in this medication guide. Slideshow Think Before You Ink: Health Risks Associated With Tattoos What is the most important information I should know about daclatasvir? Serious drug interactions can occur when certain medicines are used together with daclatasvir. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using. If you have ever had hepatitis B, daclatasvir can cause this condition to come back or get worse. You will need frequent blood tests to check your liver function. What should I discuss with my healthcare provider before taking daclatasvir? You should not use daclatasvir if you are allergic to it. If you take daclatasvir with sofosbuvir : There may be other reasons you should not take this combination treatment. Tell your doctor about all your medical conditions. Some medicines can interact with daclatasvir and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs: rifampin; St. John's wort; or seizure medicine--carbamazepine, phenytoin. To make sure daclatasvir is safe for you, tell your doctor if you have: a history of hepatitis B; liver problems other than hepatitis; heart disease; if you also use amiodarone (a heart rhythm medicine); or if you have received a liver transplant. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether daclatasvir passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Daclatasvir is not approved for use by anyone younger than 18 years old. How should I take daclatasvir? Daclatasvir is usually taken for 12 weeks. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Daclatasvir must be given in combination with sofosbuvir and it should not be used alone. You may take daclatasvir with or without food. You will need frequent blood tests to check your liver function. Read the medication guide or patient instructions provided with each medication in your combination therapy. Do not change your doses or medication schedule without your doctor's advice. Every person with chronic hepatitis C should remain under the care of a doctor. You should not stop using daclatasvir suddenly. Stopping suddenly could make your condition harder to treat with hepatitis C antiviral medicine. If you have ever had hepatitis B, daclatasvir can cause this condition to come back or get worse. You will need liver function tests during treatment and for several months after you stop using this medicine. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking daclatasvir? Taking daclatasvir will not prevent you from passing hepatitis C to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HCV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person. Daclatasvir side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. If you take daclatasvir with sofosbuvir and you also take a heart rhythm medicine called amiodarone : This combination of medicines can cause dangerous side effects on your heart. Get medical help right away if you take these medicines and you have: very slow heartbeats; chest pain, shortness of breath; or a light-headed feeling, like you might pass out. Call your doctor at once if you have serious side effects of daclatasvir, including: confusion, memory problems; severe dizziness; weakness, tiredness; or general ill feeling. Common side effects may include: headache; or feeling weak or tired. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Side Effects (complete list) Daclatasvir dosing information Usual Adult Dose for Chronic Hepatitis C: 60 mg orally once a day Recommended Regimen and Duration of Therapy: Genotype 1: -Without cirrhosis: Daclatasvir plus sofosbuvir for 12 weeks -Compensated (Child-Pugh A) cirrhosis: Daclatasvir plus sofosbuvir for 12 weeks -Decompensated (Child-Pugh B or C) cirrhosis: Daclatasvir plus sofosbuvir plus ribavirin for 12 weeks -Posttransplant: Daclatasvir plus sofosbuvir plus ribavirin for 12 weeks Genotype 3: -Without cirrhosis: Daclatasvir plus sofosbuvir for 12 weeks -Compensated (Child-Pugh A) or decompensated (Child-Pugh B or C) cirrhosis: Daclatasvir plus sofosbuvir plus ribavirin for 12 weeks -Posttransplant: Daclatasvir plus sofosbuvir plus ribavirin for 12 weeks Comments: -Dose recommendations also apply to HCV/HIV-1-coinfected patients. -Optimal duration of therapy has not been established for HCV genotype 3-infected patients with cirrhosis or for HCV genotype 1-infected patients with Child-Pugh C cirrhosis. -The manufacturer product information for sofosbuvir should be consulted regarding dosing. The manufacturer product information should be consulted regarding ribavirin dosing and dose adjustments (if applicable). Use: With sofosbuvir (with or without ribavirin), for the treatment chronic HCV genotype 1 or 3 infection What other drugs will affect daclatasvir? When you start or stop taking daclatasvir , your doctor may need to adjust the doses of any other medicines you take on a regular basis. Many drugs can interact with daclatasvir, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with daclatasvir. Give a list of all your medicines to any healthcare provider who treats you. Next Side Effects Print this page Add to My Med List More about daclatasvir Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Español 10 Reviews Add your own review/rating Drug class: NS5A inhibitors Consumer resources Daclatasvir Daclatasvir (Advanced Reading) Other brands: Daklinza Professional resources Daclatasvir Dihydrochloride (AHFS Monograph) Daclatasvir (Wolters Kluwer) Related treatment guides Hepatitis C Where can I get more information? Your pharmacist can provide more information about daclatasvir. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2012 Cerner Multum, Inc. Version: 1.04. Date modified: December 03, 2017 Last reviewed: October 06, 2016} Drug Status Rx Availability Prescription only N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class NS5A inhibitors Related Drugs Hepatitis C Harvoni , Epclusa , ribavirin , Zepatier , Mavyret , Sovaldi , sofosbuvir , ledipasvir / sofosbuvir , Vosevi , Viekira Pak , Daklinza , Pegasys , Intron A , Ribasphere , Olysio , sofosbuvir / velpatasvir , Rebetol , simeprevir , Moderiba , PegIntron , elbasvir / grazoprevir , glecaprevir / pibrentasvir , RibaPak , More... Daclatasvir Rating 10 User Reviews 9.8 /10 10 User Reviews 9.8 Rate it! Related Questions & Answers How much does Daklinza cost? Hello all, I accidentally took an extra dose of Daclatasvir by accident, 6 hours apart. I'm? Read more questions} } all of a sudden
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