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extraordinary Macitentan Generic Name: Macitentan (ma si TEN tan) Brand Name: Opsumit Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings User Reviews Support Group Q & A Warning This medicine may cause harm to the unborn baby if you take it while you are pregnant. Do not take macitentan if you are pregnant. A pregnancy test will be done to show that you are NOT pregnant before starting this medicine. A pregnancy test will be done every month during care and for 1 month after care ends. Use 2 kinds of birth control that you can trust during care and for 1 month after care ends. Females may only get macitentan through a special program. Talk with your doctor. Uses of Macitentan: It is used to treat high blood pressure in the lungs. Slideshow Cialis: 7 Important Things You Need to Know What do I need to tell my doctor BEFORE I take Macitentan? If you have an allergy to macitentan or any other part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have anemia. If you have a health problem called pulmonary veno-occlusive disease (PVOD). If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with macitentan, like certain drugs that are used for HIV, infections, or seizures. There are many drugs that must not be taken with this medicine. If you are breast-feeding. Do not breast-feed while you take macitentan. This is not a list of all drugs or health problems that interact with this medicine. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take macitentan with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Macitentan? For all patients taking this medicine: Tell all of your health care providers that you take macitentan. This includes your doctors, nurses, pharmacists, and dentists. Have blood work checked as you have been told by the doctor. Talk with the doctor. Low red blood cell levels have happened with this medicine. Sometimes, this has led to anemia and the need for a blood transfusion. If you have anemia or have been told that you have a low red blood cell level, talk with your doctor. Swelling and extra fluid in the body have happened with macitentan. Some people have had to take other drugs to treat this. Sometimes, people have had to go to the hospital to be treated for heart failure. Talk with the doctor. This medicine may affect sperm in men. This may affect being able to father a child. Talk with the doctor. If you are a woman and you miss a period, have unprotected sex, or think that your birth control has not worked, call your doctor right away. If you get pregnant while taking this medicine or within 1 month after your last dose, call your doctor right away. Children: If your child started taking macitentan before puberty, talk with the doctor. Call the doctor right away if breast buds or pubic hair begin to develop or if your child starts her menstrual period. How is this medicine (Macitentan) best taken? Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take with or without food. Swallow whole. Do not chew, break, or crush. To gain the most benefit, do not miss doses. Keep taking macitentan as you have been told by your doctor or other health care provider, even if you feel well. What do I do if I miss a dose? Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Dosage Information (comprehensive) What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain. Feeling very tired or weak. Trouble breathing that is new or worse. Shortness of breath, a big weight gain, or swelling in the arms or legs. Cough. What are some other side effects of Macitentan? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. Nose and throat irritation. Stuffy nose. Sore throat. Flu-like signs. Irritation of the airways (bronchitis). These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch. Side Effects (complete list) If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Macitentan? Store at room temperature. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Check with your pharmacist about how to throw out unused drugs. Consumer Information Use and Disclaimer If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine is refilled. If you have any questions about macitentan, please talk with the doctor, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about macitentan. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using macitentan. Review Date: November 1, 2017 Next Side Effects Print this page Add to My Med List More about macitentan Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En EspaƱol 2 Reviews Add your own review/rating Drug class: agents for pulmonary hypertension Consumer resources Macitentan Macitentan (Advanced Reading) Other brands: Opsumit Professional resources Macitentan (AHFS Monograph) Macitentan (Wolters Kluwer) Related treatment guides Pulmonary Hypertension} Drug Status Rx Availability Prescription only X Pregnancy Category Not for use in pregnancy N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Macitentan Rating 2 User Reviews 10 /10 2 User Reviews 10 Rate it! 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