gains Vigabatrin Side Effects Overview Side Effects Dosage Professional Interactions More Pregnancy Warnings Breastfeeding Warnings User Reviews Support Group Q & A For the Consumer Applies to vigabatrin: oral powder, oral powder for solution, oral tablet Along with its needed effects, vigabatrin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking vigabatrin: More common Blue-yellow color blindness blurred vision decreased vision or other vision changes eye pain increase in seizures loss of memory problems with memory Less common or rare Uncontrolled rolling eye movements Get emergency help immediately if any of the following symptoms of overdose occur while taking vigabatrin: Symptoms of overdose Change in or loss of consciousness Some side effects of vigabatrin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Agitation burning, tingling, or prickly sensations clumsiness or unsteadiness confusion constipation diarrhea dizziness double vision or seeing double increased movement joint pain mental depression sleepiness or unusual drowsiness stomach pain trembling tremor trouble sitting still Less common Aggression headache increased saliva muscle weakness nausea poor concentration speech disorder trouble sleeping unusual thoughts vomiting weight gain For Healthcare Professionals Applies to vigabatrin: oral powder for reconstitution, oral tablet Ocular Very common (10% or more): Visual field defect (30% or more of patients can be affected with bilateral concentric visual field constriction ranging in severity from mild to severe), nystagmus (up to 19%), blurred vision (up to 16%), diplopia (up to 16%) Common (1% to 10%): Asthenopia, eye pain, strabismus, conjunctivitis Rare (0.01% to 0.1%): Retinal disorder (such as peripheral retinal atrophy) Very rare (less than 0.01%): Optic neuritis, optic atrophy [ Ref ] Dermatologic Common (1% to 10%): Acne Uncommon (0.1% to 1%): Rash Rare (less than 0.1%): Angioedema, urticaria [ Ref ] Gastrointestinal Very common (10% or more): Diarrhea (up to 16%), nausea (up to 10%) Common (1% to 10%): Vomiting, abdominal pain, upper abdominal pain, constipation, dyspepsia, stomach discomfort, toothache, abdominal distention, thirst [ Ref ] General -Visual field defects ranging from mild to severe have been reported frequently in patients receiving this drug. Severe cases are potentially disabling. The onset is usually after months to years of therapy. One-third of patients receiving therapy with this drug develop visual field defects. -Approximately 50% of patients in clinical studies have experienced undesirable effects during treatment. In adults, these were mostly central nervous system related such as sedation, drowsiness, fatigue, and impaired concentration. Excitation or agitation is frequent in children. The incidence of these undesirable effects is generally higher at the beginning of treatment and decreases with time. -Some patients may experience an increase in seizure frequency, including status epilepticus with this drug. Patients with myoclonic seizures may be particularly liable to this effect. New onset myoclonus and exacerbation of existing myoclonus may occur in rare cases. [ Ref ] Genitourinary Common (1% to 10%): Urinary tract infection, dysmenorrhea, erectile dysfunction [ Ref ] Hepatic Very rare (less than 0.01%): Hepatitis Frequency not reported: Decreases in ALT and AST [ Ref ] Metabolic Very common (10% or more): Weight gain (up to 14%) Common (1% to 10%): Increased appetite [ Ref ] Musculoskeletal Very common (10% or more): Arthralgia Common (1% to 10%): Joint sprain, muscle strain, back pain, pain in extremity, myalgia, muscle twitching, muscle spasms [ Ref ] Nervous system Very common (10% or more): Headache (up to 33%), somnolence (up to 26%), dizziness (up to 26%), tremor (up to 16%), memory impairment (up to 16%), abnormal coordination (up to 16%) Common (1% to 10%): Speech disorder, sensory disturbance, paresthesia, movement disorder (including dystonia, dyskinesia, and hypertonia), either alone or in association with abnormalities in MRI, hyperreflexia, hyporeflexia, hyperesthesia, hypoesthesia, status epilepticus, dysarthria, postical state, sensory loss Uncommon (0.1% to 1%): Coordination abnormal (ataxia) Rare (0.01% to 0.1%): Encephalopathy (e.g., sedation, stupor, confusion) Very rare (less than 0.01%): Optic neuritis, optic atrophy (see also OCULAR) Frequency not reported: Increase in seizure frequency [ Ref ] Other Very common (10% or more): Fatigue (up to 40%), gait disturbance (up to 12%) Common (1% to 10%): Edema, tinnitus, vertigo, peripheral edema [ Ref ] Psychiatric Very common (10% or more): Excitation (children), agitation (children) Common (1% to 10%): Agitation, aggression, nervousness, depression, paranoid reaction, irritability, asthenia, fever, thirst, malaise, expressive language disorder, abnormal dreams, mental impairment (thought disturbance), lethargy, disturbance in attention Uncommon (0.1% to 1%): Hypomania, mania, psychotic disorder Rare (0.01% to 0.1%): Suicide attempt Very rare (less than 0.01%): Hallucination [ Ref ] Respiratory Very common (10% or more): Upper respiratory tract infection (up to 51%) Nasopharyngitis (up to 14%), pharyngeal pain (up to 14%), cough (up to 14%) Common (1% to 10%): Bronchitis, pulmonary congestion, sinus headache [ Ref ] Cardiovascular Common (1% to 10%): Chest pain [ Ref ] Hematologic Common (1% to 10%): Anemia [ Ref ] Immunologic Very common (10% or more): Viral infection (up to 20%), pneumonia (up to 13%) Common (1% to 10%): Influenza Uncommon (0.1% to 1%): Candidiasis, ear infection, croup infectious [ Ref ] References 1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 2. Cerner Multum, Inc. "Australian Product Information." O 0 3. "Product Information. Sabril (vigabatrin)." Lundbeck Inc, Deerfield, IL. Some side effects of vigabatrin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA . Next Dosage Print this page More about vigabatrin Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Interactions Support Group En Español 0 Reviews Add your own review/rating Drug class: gamma-aminobutyric acid analogs Consumer resources Vigabatrin Vigabatrin Tablets Vigabatrin Oral Solution Vigabatrin (Advanced Reading) Other brands: Sabril Professional resources Vigabatrin (AHFS Monograph) Vigabatrin (FDA) Vigabatrin (Wolters Kluwer) Related treatment guides Epilepsy Seizure Prevention Seizures Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.} Drug Status Rx Availability Prescription only C Pregnancy Category Risk cannot be ruled out N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Drug Class Gamma-aminobutyric acid analogs Related Drugs Epilepsy gabapentin , Lyrica , Neurontin , lamotrigine , levetiracetam , Lamictal , Depakote , Keppra , More... Seizures diazepam , levetiracetam , topiramate , Valium , Topamax , Keppra , primidone , Dilantin , More... Seizure Prevention clonazepam , diazepam , Klonopin , lamotrigine , topiramate , Valium , Topamax , Lamictal , More... Vigabatrin Rating No Reviews - Be the first! 4.0 /10 No Reviews - Be the first! 4.0 Rate it!} } for toilet
surgery Vigabatrin Side Effects understand
EmoticonEmoticon