gave the look of Dicyclomine Pregnancy and Breastfeeding Warnings Dicyclomine is also known as: Bemote, Bentyl , Bentyl Syrup, Byclomine, Di-Spaz, Dibent, Dicyclocot, Dilomine Overview Side Effects Dosage Professional Tips More Interactions Pregnancy Warnings Breastfeeding Warnings User Reviews Drug Images Support Group Q & A Compare Alternatives Pricing & Coupons Dicyclomine Pregnancy Warnings Animal studies in rats and rabbits have revealed no evidence of harm to the fetus with this drug. Adequate and well-controlled studies have not been conducted in pregnant women. US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. US FDA pregnancy category: B See references Dicyclomine Breastfeeding Warnings Use should be avoided. Excreted into human milk: Yes Excreted into animal milk: Data not available Comments: A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother. A single case has been reported of a breast-fed 12 day old infant who developed apnea whose mother was receiving dicyclomine. A causal relationship between dicyclomine and apnea could not be confirmed. Similar adverse reactions have occurred with direct administration of dicyclomine to infants. See references References for pregnancy information Williams J, Watkins-Jones R "Dicyclomine: worrying symptoms associated with its use in some small babies." Br Med J (Clin Res Ed) 288 (1984): 901 Huff PS "Safety of drug therapy for nausea and vomiting of pregnancy." J Fam Pract 11 (1980): 969-70 Altman PM "Debendox withdrawn." Med J Aust 140 (1984): 119 Congenital Abnormalities Sub-Committee of the Australian Drug Evaluation Committtee "Debendox in pregnancy." Med J Aust 1 (1980): 197 Miklovich L, van den Berg BJ "An evaluation of the teratogenicity of certain antinauseant drugs." Am J Obstet Gynecol 125 (1976): 244-8 Correy JF, Newman NM "Debendox and limb reduction deformities." Med J Aust 1 (1981): 417-8 Correy JF, Newman NM "Debendox withdrawn." Med J Aust 140 (1984): 796-7 DonnaiD, Harris R "Unusual fetal malformations after antiemetics in early pregnancy." Br Med J 1 (1978): 691-2 Sheffield LJ, Batagol R "The creation of therapeutic orphans--or, what have we learnt from the Debendox fiasco?" Med J Aust 143 (1985): 143-7 Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 Gordon I "Debendox." Med J Aust 144 (1986): 51-2 Mellor S "Fetal malformation after debendox treatment in early pregnancy." Br Med J 1 (1978): 1055 Patterson DC "Congenital deformities associated with Benedectin." Can Med Assoc J 116 (1977): 1348 Fleming DM, Knox JD, Crombie DL "Debendox in early pregnancy and fetal malformation." Br Med J (Clin Res Ed) 283 (1981): 99-101 Wheatley D "Treatment of pregnancy sickness." Br J Obstet Gynaecol 84 (1977): 444-7 Cordero JF, Oakley GP Jr "Drug exposure during pregnancy: some epidemiologic considerations." Clin Obstet Gynecol 26 (1983): 418-28 "Product Information. Bentyl (dicyclomine)." Aventis Pharmaceuticals, Kansas City, MO. Dickson JH "Congenital deformities associated with bendectin." Can Med Assoc J 117 (1977): 721-2 Morelock S, Hingson R, Kayne H, Dooling E, Zuckerman B, Day N, Alpert JJ, Flowerdew G "Bendectin and fetal development. A study of Boston City Hospital." Am J Obstet Gynecol 142 (1982): 209-13 Smithells RW, Sheppard S "Fetal malformation after debendox treatment in early pregnancy." Br Med J 1 (1978): 1055-6 Harris R, Donnai D "Debendox and the media." Br Med J 280 (1980): 480-1 Harron DW, Griffiths K, Shanks RG "Debendox and congenital malformations in Northern Ireland." Br Med J 281 (1980): 1379-81 Shapiro S, Heinonen OP, Siskind V, Kaufman DW, Monson RR, Slone D "Antenatal exposure to doxylamine succinate and dicyclomine hydrochloride (Benedectin) in relation to congenital malformations, perinatal mortality rate, birth weight, and intelligence quotient score." Am J Obstet Gynecol 128 (1977): 480-5 Golden SM, Perman KI "Bilateral clinical anophthalmia: drugs as potential factors." South Med J 73 (1980): 1404-7 Gibson GT, Colley DP, McMichael AJ, Hartshorne JM "Congenital anomalies in relation to the use of doxylamine/dicyclomine and other antenatal factors: an ongoing prospective study." Med J Aust 1 (1981): 410-4 Mitchell AA "Debendox." Med J Aust 144 (1986): 52 Maling TJ "Debendox: a statement from the New Zealand Adverse Drug Reactions Committee." N Z Med J 97 (1984): 203-4 References for breastfeeding information "Product Information. Bentyl (dicyclomine)." Aventis Pharmaceuticals, Kansas City, MO. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998): Print this page See Also... Dicyclomine use while Breastfeeding (in more detail) dicyclomine Consumer Information Pregnancy Support Group FDA Pregnancy Categories Medicine use during Pregnancy Medicine use while Breastfeeding Safe Medications during Breastfeeding Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist. Drug Status Rx Availability Prescription only B Pregnancy Category No proven risk in humans N/A CSA Schedule Not a controlled drug Approval History Drug history at FDA Dicyclomine Rating 162 User Reviews 7.8 /10 162 User Reviews 7.8 Rate it! Drug Class Anticholinergics / antispasmodics Related Questions & Answers Dicyclomine - Can I continue taking my Calcium and B12 vitamins? Also, my doctor perscribed? Please can anybody tell me about this medication dicyclomine 20 mg Ok? Abdominal Adhesions - OK I BEEN TOLD BY SURGEON THAT HAVE SEVEE ADHESION FROM PAST MAJOR ABDOMAL? Can you take Dicyclomine and then take a tablet of Acidophilus to restore the flora in the gut? Is dicyclomine hydrochroride..spansmindon safe for period pain? Read more questions i assumed
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