more healthy [2:40 C. b Tight containers; avoid exposure to excessive heat. d Emulsions also should be protected from freezing. b Actions Castor oil, a stimulant laxative, is a fixed oil obtained from the seeds of Ricinus communis Linné. b d Aromatic castor oil is a solution of castor oil in alcohol containing suitable flavoring agents. b d Aromatic castor oil contains not less than 95% castor oil and not more than 4% alcohol. b d Ricinoleic acid, which is produced by hydrolysis via pancreatic lipase in the small intestine, is responsible for castor oil s laxative action. e Precise mechanism unknown. e Commonly thought that stimulant laxatives induce defecation by stimulating propulsive peristaltic activity of the intestine through local irritation of the mucosa or through a more selective action on the intramural nerve plexus of intestinal smooth muscle, thus increasing motility. c e More recent evidence shows that stimulant laxatives alter fluid and electrolyte absorption, producing net intestinal fluid accumulation and laxation. c Stimulant laxatives mainly promote evacuation of the colon; however, castor oil also directly or reflexly increases activity of the small intestine. c Castor oil produces violent purgation in therapeutic doses. c Advice to Patients Importance of not taking castor oil at bedtime since the laxative effect occurs quickly. e Advise patients that prolonged use can cause excessive loss of fluids, electrolytes, and nutrients. e Importance of not using laxative products for a period longer than 1 week unless directed by a clinician. c Importance of informing clinicians before use if abdominal pain, nausea, or vomiting is present or if a sudden change in bowel habits that persists over a period of 2 weeks has been noticed. a c Advise about risk of laxative abuse and potential serious consequences. c e (See Chronic Use or Overdosage under Cautions.) Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs as well as any concomitant illnesses. Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed. c e Importance of informing patients of other important precautionary information. (See Cautions.) Preparations Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details. Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations. * available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name Castor Oil Routes Dosage Forms Strengths Brand Names Manufacturer Oral Oil* 95% w/v* Purge Fleming Suspension 36.4% w/w Neoloid (with propylene glycol) Kenwood 95% w/v* Emulsoil Paddock Purge Fleming * available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name Castor Oil Aromatic Routes Dosage Forms Strengths Brand Names Manufacturer Oral Oil* Castor Oil Aromatic Roxane AHFS DI Essentials. Copyright 2017, Selected Revisions May 1, 2004. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814. References a. Fleming & Co. Purge (flavored castor oil) stimulant laxative prescribing information. Fenton, MO; undated. b. AHFS drug information 2004. McEvoy GK, ed. Castor Oil. Bethesda, MD: American Society of Health-System Pharmacists; 2004:2775. c. AHFS Drug Information 2004. McEvoy, GK, ed. Cathartics and laxatives general statement. Bethesda, MD: American Society of Health-System Pharmacists; 2004:2769-73 d. The United States pharmacopeia, 27th rev, and The national formulary, 22nd ed. Rockville, MD: The United States Pharmacopeial Convention, Inc; 2004:348-9. e. American Pharmaceutical Association. Handbook of nonprescriptin drugs. 14th ed. Washington, DC: American Pharmaceutical Association; 2004:380,384-6,1339. f. CB Fleet Co. Fleet Prep Kits (bowel evacuant) prescribing information. Lynchburg, VA; undated. Next Interactions Print this page Add to My Med List More about castor oil Drug Interactions Support Group Pricing & Coupons 0 Reviews Add your own review/rating Drug class: laxatives] FEATURED: CAR-T Cell Therapy Overview Mechanism of Action KTE-C19 Studies KTE-C19 Cancer Targets Adverse Events Manufacturing Drug Status OTC Availability Over the counter X Pregnancy Category Not for use in pregnancy N/A CSA Schedule Not a controlled drug Drug Class Laxatives Recently Approved Lonhala Magnair Lonhala Magnair (glycopyrrolate) is a long-acting muscarinic antagonist (LAMA) bronchodilator for... Ozempic Ozempic (semaglutide) is a glucagon-like peptide-1 (GLP-1) analog administered once-weekly for the... Ogivri Ogivri (trastuzumab-dkst) is a HER2 / neu receptor antagonist biosimilar to Herceptin indicated for... Sublocade Sublocade (buprenorphine) is a once-monthly injectable partial opioid agonist formulation for the... More Castor oil Rating No Reviews - Be the first! 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